AI Article Synopsis
- Pruritus, or itch, is a common symptom linked to various skin and systemic disorders, classified into four categories: neuropathic, neurogenic/systemic, psychogenic, and pruritoceptive.
- An 83-year-old man experienced generalized pruritus caused by cholestasis due to bile duct cancer, with unusual symptoms, including skin eruptions after starting meloxicam.
- Healthcare providers should investigate systemic causes of pruritus when patients display atypical skin reactions, as proper classification can aid in treatment and diagnosis.
Article Abstract
Pruritus, colloquially known as itch, is a common clinical symptom seen in a variety of dermatological conditions and systemic disorders. Pruritus can broadly be classified into four categories: neuropathic, neurogenic/systemic, psychogenic, and pruritoceptive. Initial categorization depends on anatomical and pathophysiological aspects of presentation and is reflective of underlying etiology. We report a case of an 83-year-old man presenting with generalized pruritus secondary to cholestasis from bile duct malignancy. This case is notable for atypical presenting features, including a trunk eruption comprised of excoriated papules with onset following meloxicam initiation, mimicking a cutaneous adverse drug reaction. Providers should consider systemic etiologies of pruritus in patients presenting with cutaneous eruptions with atypical features. Accurate categorization of pruritus can facilitate treatment and/or additional investigation of systemic disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729841 | PMC |
| http://dx.doi.org/10.7759/cureus.49049 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dermal CIC-Rearranged Sarcoma With Neuroendocrine Differentiation Mimicking Merkel Cell Carcinoma.
J Cutan Pathol
December 2024
SkinPath Solutions, Smyrna, Georgia, USA.
Capicua transcriptional repressor (CIC)-rearranged sarcoma (CRS) is a rare and recently described tumor that most commonly affects patients between 15 and 30 years of age. It is an undifferentiated round cell malignancy, with a disease defining CIC fusion, with double homeobox 4 (DUX4) being the most common partner. Here, we report a 77-year-old woman who presented with a cutaneous thigh mass with a clinical morphology suggesting Merkel cell carcinoma.
View Article and Find Full Text PDFSalmon colored fluorescence on Wood's lamp in a pediatric patient with vitiligo: A case report.
J Family Med Prim Care
November 2024
Department of Dermatology, King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.
Vitiligo, a prevalent cutaneous depigmentation disorder, often leads individuals to seek cosmetic remedies such as dihydroxyacetone (DHA)-infused camouflage makeup. Wood's lamp, a common diagnostic tool in dermatology, is typically employed to assess vitiligo lesions, revealing DHA-induced fluorescence in a distinct salmon color, contrasting with the bright blue-white fluorescence exhibited by vitiligo lesions. Erythrasma, a bacterial infection of the epidermis, is known for its unique bright coral-pink or coral-red fluorescence under Wood's lamp.
View Article and Find Full Text PDFA20 haploinsufficiency diagnosis beyond systemic lupus erythematosus: A systematic review of the literature.
Autoimmun Rev
December 2024
Department of Clinical Immunology and Internal Medicine, CHU of Caen Normandie, 14000 Caen, France; Normandie Univ, UNICAEN, CHU de Caen Normandie, 14000 Caen, France.
Systemic lupus erythematosus (SLE) is an autoimmune disease whose pathophysiology remains incompletely understood, involving genetic and epigenetic factors. However, an increasing small subset of patients present with monogenic lupus, providing insight into the pathogenesis of the disease. This systematic review focuses on SLE associated with A20 haploinsufficiency (HA20), a monogenic disorder associated with tumor necrosis factor alpha-induced protein 3 gene (TNFAIP3) variants.
View Article and Find Full Text PDFGranulomatosis with polyangiitis mimicking multisystem pyoderma gangrenosum: A case report.
SAGE Open Med Case Rep
December 2024
Division of Clinical Dermatology and Cutaneous Science, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Granulomatosis with polyangiitis, a type of small-medium vessel vasculitis, can pose diagnostic challenges due to its diverse clinical manifestations. We present a case that mimicked multisystem pyoderma gangrenosum with cutaneous ulceration, renal sparing, and antineutrophil cytoplasmic antibody negativity. Although antineutrophil cytoplasmic antibody is positive in approximately 90% of cases of granulomatosis with polyangiitis, its negativity should not exclude the diagnosis.
View Article and Find Full Text PDFKodamaea ohmeri infection can be the causative agent of secondary infections of intertrigo: A case study.
J Dermatol
December 2024
Institute of Dermatology and Venereal Diseases, Department of Dermatology and Venereal Diseases, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Kodamaea ohmeri infection is a relatively rare condition, primarily affecting immunocompromised individuals or those with a history of invasive procedures. The diagnosis of this infection is challenging because of its diverse and complex atypical clinical presentations. In this study, we describe a case of cutaneous infection with Kodamaea ohmeri presenting as erythematous and scaly lesions on both armpits and groin with itching in an 82-year-old man, mimicking intertrigo, and review the relevant literature.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!