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http://dx.doi.org/10.1038/s41408-023-00963-y | DOI Listing |
Ann Oncol
September 2024
Department of Medicine, Immunology and Allergy Service. Electronic address:
Transplant Cell Ther
November 2024
Stanford University School of Medicine, Stanford, California.
Hemasphere
July 2024
Department of Hematology, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Leuk Lymphoma
September 2024
Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA, USA.
AMG 330, a bispecific T-cell engager (BiTE®) that binds CD33 and CD3 on T cells facilitates T-cell-mediated cytotoxicity against CD33+ cells. This first-in-human, open-label, dose-escalation study evaluated the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of AMG 330 in adults with relapsed/refractory acute myeloid leukemia (R/R AML). Amongst 77 patients treated with AMG 330 (0.
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