Introduction: The purpose of this retrospective registry-based study is to assess survival and causes of failure of cementless stem implants used in total hip arthroplasty (THAs), to ascertain if there are differences when these are categorized according to the six types described by Mont.
Methods: Data collected from the regional registry regarding all primary THAs performed from 2000 to 2019 were analyzed. Femoral prosthetic stems were divided into the six types of Mont classification. For each stem type, number of implants, survival and causes of failure were evaluated and compared.
Results: The most frequently implanted stem type was the 3c type (53.4%). Type 1 had the lowest stem failure rate (1.6%), and type 6 showed the highest (3.9%). Periprosthetic fracture was the most frequent complication in type 6, accounting for 34.5% of failures. Aseptic loosening was the main complication in type 2 stems, accounting for 36.4% of failures. Pairwise comparisons showed significant higher survival of type 1 compared to type 3c (p = 0.000026) and type 6 (p = 0.000076), and between type 3a compared to type 3c (p = 0.03) and type 6 (p = 0.026).
Conclusion: Significant variations in implant survival rates were found among the six Mont-types of cementless stems. These findings emphasize the paramount importance of stem design and fixation area in determining long-term survival, providing a guidance for orthopedic surgeons in the selection of the most appropriate stem for primary THA, contributing to our understanding of cementless stem performance, presenting invaluable insights to further improve patient outcomes in THA surgery.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s00402-023-05144-x | DOI Listing |
FASEB J
March 2025
Department of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Neuron-derived clone 77 (Nur77), a member of the orphan nuclear receptor family, is expressed and activated rapidly in response to diverse physiological and pathological stimuli. It exerts complex biological functions, including roles in the nervous system, genome integrity, cell differentiation, homeostasis, oxidative stress, autophagy, aging, and infection. Recent studies suggest that Nur77 agonists alleviate symptoms of neurodegenerative diseases, highlighting its potential as a therapeutic target in such conditions.
View Article and Find Full Text PDFFASEB J
March 2025
Department of Oncology, The Central Hospital of Yongzhou, Yongzhou, Hunan, China.
The ribophorin family, including RPN1, has been associated with tumor progression, but its specific role in pan-cancer dynamics remains unclear. Using data from TCGA, GTEx, and Ualcan databases, we investigated the relationship of RPN1 with prognosis, genomic alterations, and epigenetic modifications across various cancers. Differential analysis revealed elevated RPN1 expression in multiple cancer types, indicating a potential prognostic value.
View Article and Find Full Text PDFCancer Med
March 2025
Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.
Introduction: Distress is common among cancer patients, especially those undergoing surgery. However, no study has systematically analyzed distress trends in this population. The purpose of this study was to systematically review perioperative rates of distress, as well as differences across cancer types, in cancer patients undergoing surgical intervention.
View Article and Find Full Text PDFDalton Trans
March 2025
Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
This study presents the direct -alkylation of aromatic amines using greener primary alcohols as alkyl donors, catalyzed by base metal-derived Co(II) catalysts the borrowing hydrogen (BH) method. Two well-defined phosphine-free NNN-type pincer ligands (L1 and L2) were synthesized and utilized to prepare cobalt(II) catalysts C1 and C2. The catalysts were well characterized by UV-vis, IR, HRMS, and single-crystal X-ray diffraction studies.
View Article and Find Full Text PDFLangmuir
March 2025
School of Material Science and Engineering, University of Jinan, Jinan, 250022, PR China.
The construction of heterostructures promotes extending the light adsorption range of graphitic carbon nitride (g-CN) materials, improving the photogenerated charge carrier separation/transfer efficiency for attaining much enhanced performances. Because defective tungsten oxide (WO) materials possess rich composition/morphology and an extended light response in the near-infrared region, WO is a quite popular nanocomponent for modifying g-CN, forming heterostructures that can be used for various photocatalytic applications involving water splitting, CO reduction, NO removal, HO generation, and related chemical to fuel conversion reactions. In this review, important aspects of WO/g-CN heterostructure photocatalysts are reviewed to provide paradigms for composition adjustment, structural design, and photocatalytic applications of these materials.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!