AI Article Synopsis
- Nanoparticles designed for delivering thrombolytic drugs are being developed to improve targeted treatment for thrombosis, a condition involving blood clots.
- There’s a growing focus on magnetic nanoparticles, which can be controlled using magnetic fields, but there’s limited literature on their use in thrombolysis.
- The study reviews the use of magnetic nanoparticles in thrombolysis, detailing four key processes, and aims to provide insights for future research and clinical applications in this area.
Article Abstract
Nanoparticles containing thrombolytic medicines have been developed for thrombolysis applications in response to the increasing demand for effective, targeted treatment of thrombosis disease. In recent years, there has been a great deal of interest in nanoparticles that can be navigated and driven by a magnetic field. However, there are few review publications concerning the application of magnetic nanoparticles in thrombolysis. In this study, we examine the current state of magnetic nanoparticles in the application of and thrombolysis under a static or dynamic magnetic field, as well as the combination of magnetic nanoparticles with an acoustic field for dual-mode thrombolysis. We also discuss four primary processes of magnetic nanoparticles mediated thrombolysis, including magnetic nanoparticle targeting, magnetic nanoparticle trapping, magnetic drug release, and magnetic rupture of blood clot fibrin networks. This review will offer unique insights for the future study and clinical development of magnetic nanoparticles mediated thrombolysis approaches.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10727495 | PMC |
| http://dx.doi.org/10.1109/ojnano.2023.3273921 | DOI Listing |
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