Objective: To determine sex differences in the prevalence of depression and assess the risk factors for depression among adult patients with epilepsy from the Dali area of China.
Methods: We retrospectively analyzed the clinical data of adult patients with epilepsy who visited the First Affiliated Hospital of Dali University from January 2017 to January 2022. Patient Health Questionnaire-9 was used to assess depressive symptoms in patients with epilepsy. The risk factors of depression were analyzed by binary logistic regression among different sex in patients with epilepsy.
Results: There were significant sex differences in depression in patients with epilepsy ( 0.001), and females were 4.27 times more likely to suffer from depression than males (95% confidence interval: 3.70-4.92). The risk factors for depression among female patients with epilepsy included occupation ( 0.001), years with epilepsy ( 0.001), seizure frequency ( 0.001), seizure type ( 0.001), etiology ( 0.001), number of antiseizure medications used ( 0.001), antiseizure medications ( 0.001), and electroencephalogram findings ( 0.001). The risk factors for depression among male patients with epilepsy included age ( 0.001), ethnicity ( 0.001), occupation ( 0.001), years with epilepsy ( 0.001), seizure frequency ( 0.001), seizure type ( 0.001), etiology ( 0.001), number of antiseizure medications used ( < 0.001), antiseizure medications ( 0.001), and electroencephalogram findings ( 0.001).
Conclusion: Adult female patients with epilepsy had a higher risk of depression than adult male patients with epilepsy. There were sex differences in the risk factors associated with depression among patients with epilepsy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725914 | PMC |
| http://dx.doi.org/10.3389/fpsyt.2023.1283983 | DOI Listing |
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