Background: Solitary fibrous tumor (SFT) of the chest mainly arises from the pleura, but intrapulmonary SFT is rare. This study aimed to review and discuss the chest multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) findings of intrapulmonary SFT and summarize existing literature on the disease in order to improve clinicians' understanding and diagnosis of this disease.
Methods: The imaging findings and clinical data of 4 surgically and pathologically confirmed intrapulmonary SFT cases were retrospectively analyzed in terms of location, morphology, size, density, border, enhancement level of the lesion, and its relationship with surrounding tissue. These findings were combined with a review of 61 cases reported in the literature to characterize the features of intrapulmonary SFT.
Results: A total of 65 patients with intrapulmonary SFT were reviewed, consisting of 30 females and 35 males. Of these cases, 21 had a lesion in the left lower lobe, more than in any other part of the lungs. The lesions were clear, had a quasicircular boundary, and were distinctly separated from surrounding tissue. Under plain scan, the 4 cases investigated in this study showed lesions of even density, and enhanced scanning revealed geographic enhancement in 2 cases. Of the 65 cases examined, 56 cases were benign, and the remaining 9 cases were borderline or malignant.
Conclusions: The imaging findings of intrapulmonary SFT demonstrated certain features, such as lesions with a clear boundary and even density. Imaging examination is important for the diagnosis and differential diagnosis of this disease.
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http://dx.doi.org/10.21037/qims-22-1328 | DOI Listing |
Radiol Case Rep
January 2025
Department of Radiology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that affects most commonly in the sixth or seventh decade of life. They account for less than 2% of all soft tissue tumors. In the thoracic region, it primarily appears in the pleura and rarely in the intrapulmonary.
View Article and Find Full Text PDFAutops Case Rep
June 2024
Jagadguru Sri Shivarathreeshwara Academy of Higher Education & Research (JSSAHER), Department of Pathology, Mysore, Karnataka, India.
Solitary fibrous tumor (SFT) is a soft tissue tumor of mesenchymal origin involving, most commonly, the pleura. Intrapulmonary SFT is a slow-growing tumor that rarely reaches giant forms. SFTs are asymptomatic and often randomly discovered by routine chest X-rays.
View Article and Find Full Text PDFAnn Diagn Pathol
December 2024
Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA.
Five cases of thoracic solitary fibrous tumor (SFT) with small cell features are presented mimicking a neuroendocrine neoplasm. The patients were four men and one woman aged 43 to 74 years who presented with symptoms of chest pain, cough, dyspnea or hemoptysis. Two tumors were intrapulmonary neoplasms, while three were pleural-based.
View Article and Find Full Text PDFJ Surg Case Rep
January 2024
Department of Thoracic Surgery, Center of Cardio-Thoracic Surgery, Clinic of Chest Diseases, Immunology and Allergology, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius LT-08661, Lithuania.
Solitary fibrous tumor (SFT) is an extremely rare mesenchymal neoplasm usually detected in the pleura, which generally follows a benign course. The localization inside lung parenchyma has more rarely been reported. We present a case of a 51-year-old male with a dry cough, dyspnea, chest pain, and increased perspiration.
View Article and Find Full Text PDFQuant Imaging Med Surg
December 2023
Radiology Diagnosis Department, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Background: Solitary fibrous tumor (SFT) of the chest mainly arises from the pleura, but intrapulmonary SFT is rare. This study aimed to review and discuss the chest multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) findings of intrapulmonary SFT and summarize existing literature on the disease in order to improve clinicians' understanding and diagnosis of this disease.
Methods: The imaging findings and clinical data of 4 surgically and pathologically confirmed intrapulmonary SFT cases were retrospectively analyzed in terms of location, morphology, size, density, border, enhancement level of the lesion, and its relationship with surrounding tissue.
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