Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.

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Article Synopsis
  • Acute bacterial meningitis (ABM) poses significant health risks, primarily caused by bacteria like Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae, with complications like elevated intracranial pressure (ICP) impacting patient outcomes.
  • A review of studies highlighting the role of ICP management in ABM showed an association between high ICP levels and increased mortality, with invasive monitoring methods like external ventricular drains being most common.
  • Although evidence is limited, the review suggests potential benefits in patient outcomes when utilizing invasive ICP monitoring and management techniques, emphasizing the need for standardized treatment protocols and further research.
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[Not Available].

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Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week.

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