AI Article Synopsis
- Direct immunofluorescence (DIF) is the top method for diagnosing pemphigus, a skin condition.
- Alternative substrates like skin biopsies, anagen hair, and oral erosion scrapings can also be used for DIF testing.
- These alternative methods are less invasive and may provide easier options for young patients, as well as help in monitoring relapses of pemphigus.
Article Abstract
Direct immunofluorescence (DIF) on skin is considered as the gold standard in the diagnosis of pemphigus. However, alternate substrates can be used. We demonstrate DIF on three substrates, skin biopsy specimen, anagen hair and scrapings of oral erosions. Collection of alternative substrates can be more acceptable to young patients as it is less invasive. It may also be used to detect relapses in cases of pemphigus.
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| http://dx.doi.org/10.1111/pde.15501 | DOI Listing |
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