Associations of an individual's need for cognition with structural brain damage and cognitive functioning/impairment: cross-sectional population-based study.

Br J Psychiatry

School for Mental Health & Neuroscience (MHeNs), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands; and Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

Published: June 2024

AI Article Synopsis

  • High cognitive activity may help reduce the risk of cognitive decline and dementia, as suggested by the study.
  • The research examined the relationship between an individual's need to engage in cognitively stimulating activities (NFC) and brain health among 4209 participants, revealing that those with higher NFC scores had better cognitive functioning and lower odds of cognitive impairment and small vessel disease.
  • The findings indicate that having a strong motivation for cognitive engagement can positively impact cognitive abilities, especially in middle-aged individuals, though no significant links were found between NFC and certain brain structure measures.

Article Abstract

Background: High cognitive activity possibly reduces the risk of cognitive decline and dementia.

Aims: To investigate associations between an individual's need to engage in cognitively stimulating activities (need for cognition, NFC) and structural brain damage and cognitive functioning in the Dutch general population with and without existing cognitive impairment.

Method: Cross-sectional data were used from the population-based cohort of the Maastricht Study. NFC was measured using the Need For Cognition Scale. Cognitive functioning was tested in three domains: verbal memory, information processing speed, and executive functioning and attention. Values 1.5 s.d. below the mean were defined as cognitive impairment. Standardised volumes of white matter hyperintensities (WMH), cerebrospinal fluid (CSF) and presence of cerebral small vessel disease (CSVD) were derived from 3T magnetic resonance imaging. Multiple linear and binary logistic regression analyses were used adjusted for demographic, somatic and lifestyle factors.

Results: Participants ( = 4209; mean age 59.06 years, s.d. = 8.58; 50.1% women) with higher NFC scores had higher overall cognition scores ( = 0.21, 95% CI 0.17-0.26, < 0.001) and lower odds for CSVD (OR = 0.74, 95% CI 0.60-0.91, = 0.005) and cognitive impairment (OR = 0.60, 95% CI 0.48-0.76, < 0.001) after adjustment for demographic, somatic and lifestyle factors. The association between NFC score and cognitive functioning was similar for individuals with and without prevalent cognitive impairment. We found no significant association between NFC and WMH or CSF volumes.

Conclusions: A high need to engage in cognitively stimulating activities is associated with better cognitive functioning and less presence of CSVD and cognitive impairment. This suggests that, in middle-aged individuals, motivation to engage in cognitively stimulating activities may be an opportunity to improve brain health.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615981PMC
http://dx.doi.org/10.1192/bjp.2023.159DOI Listing

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