Abnormalities of the bovine scrotum and testes are an important cause of infertility. Proper evaluation of the male reproductive system is a critical first step in screening for such abnormalities. Excessive periscrotal fat, cutaneous scrotal defects, and unilateral scrotal swelling are common deformities that warrant further investigation. Early diagnosis and surgical intervention are often needed to restore reproductive soundness. This article reviews these conditions and provides therapeutic modalities.
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http://dx.doi.org/10.1016/j.cvfa.2023.09.003 | DOI Listing |
J Clin Med
December 2024
Department of Andrology and Reproductive Endocrinology, Medical University of Lodz, 90-419 Lodz, Poland.
The hormonal aspect of undescended testes (UDTs) in prepubertal boys, i.e., after mini-puberty, is poorly understood.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Background: Cryptorchidism is the absence of one or both testicles in the scrotum at birth, being a risk factor for testis cancer and infertility. The most effective method to treat cryptorchidism is orchiopexy, followed by human chorionic gonadotropin (hCG) therapy; however, a portion of treated patients do not show a significant improvement in testis volume and vascularization after adjuvant therapy.
Methods: In this study, we generated an in vitro model to predict the patient response to hCG by cultivating and treating primary cells derived from five cryptorchid patients' biopsies of gubernaculum testis, the ligament that connects the testicle to the scrotum.
Front Oncol
December 2024
Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Objective: To investigate the clinical and ultrasound features of fibrous pseudotumor of tunica vaginalis of the testis.
Methods: The clinical and ultrasound features of fibrous pseudotumor of the tunica vaginalis diagnosed by pathology in West China Hospital of Sichuan University from 2006 to 2023 were retrospectively analyzed.
Results: The study included 8 patients diagnosed with fibrous pseudotumor of the tunica vaginalis.
Cureus
December 2024
Radiology, Saitama Children's Medical Center, Saitama, JPN.
Objectives: Testicular torsion, a condition requiring urgent intervention, can occur at any age and present with diverse symptoms. To the best of our knowledge, no study has evaluated the characteristics of testicular torsion in childhood, a less common age group. This study showed differences in patients' characteristics between childhood and adolescence and the variation across ages.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pediatric Surgery and Urology, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
Cryptorchidism, the absence of one or both testicles in the scrotum, is the most common anomaly of genitourinary tract in males. The pathogenesis of undescended testes is unknown however the role of inflammation, tissue remodeling and oxidative stress is postulated. The aim of this study was to explore the role of HSP-70, MMP-3, MMP-17 and IL-8 in possible pathogenic pathways connected with cryptorchidism.
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