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Transperineal MR Fusion Laser Ablation of Prostate Cancer in Office Setting: 1 Year Efficacy and Safety Outcomes in Intermediate-Risk Patients.
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January 2025
Urological Research Network, Miami Lakes, Florida, USA.
Focal therapy (FT) is an emerging option for intermediate-risk prostate cancer (IR-PCa). Transperineal MRI fusion laser ablation of PCa (TPFLA) is a novel FT technique with limited data reported. We conducted a phase I clinical trial evaluating the safety, feasibility, and 1-year oncologic results for patients with IR-PCa treated with TPFLA in an office setting.
View Article and Find Full Text PDFA 36-Year-Old Patient With Crohn Disease and Bilateral Pleural Effusions.
Chest
December 2024
Division of Pulmonary, Critical Care and Sleep Medicine, University of California at Davis, Sacramento, CA.
A 36-year-old man with severe Crohn disease complicated by urethral strictures and enterocutaneous and enterovesicular fistulas presented for several weeks of poor appetite, weight loss, failure to thrive, and newly worsening altered mentation. Further history revealed he chronically did not urinate through his urethra, but rather "leaked" through multiple enterocutaneous fistulas in his abdomen and perineum. Medications included ustekinumab (anti-IL12/IL23 monoclonal antibody) for Crohn disease, methadone, and hydrocodone.
View Article and Find Full Text PDFTransperineal ultrasound evaluation of pelvic floor muscle function in male patients with constipation.
Int J Colorectal Dis
November 2024
Department of Ultrasound, Second Affiliated Hospital of Fujian Medical University, No. 34 Zhongshan North Road, Licheng District, Quanzhou, 362000, Fujian, China.
Objective: To investigate the application of transperineal ultrasound for assessing pelvic floor muscle (PFM) function in male patients with constipation and to evaluate its clinical value.
Methods: The study included 32 male patients with constipation and 32 healthy controls, all of whom underwent transperineal ultrasound examinations. Measured parameters included the anorectal angle (ARA), levator plate angle (LPA), excursions of the ARA and LPA, and displacements of the bulb of the penis (BP), mid-urethra (MU), urethra-vesical junction (UVJ), and anorectal junction (ARJ) at rest, during maximal voluntary contraction (MVC), and during maximal Valsalva maneuver.
Erectile dysfunction is an underdiagnosed consequence of low anterior resection and abdominoperineal resection for colorectal cancer.
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Department of Urology, Weill Cornell Medicine, New York, NY, USA.
To explore the frequency and predictive factors of erectile dysfunction diagnosis after colorectal cancer surgery. The Surveillance, Epidemiology, and End Results-Medicare database was used to identify a national sample of men undergoing surgery for colorectal cancer from 2004 to 2015. Men aged > 65 years with any index surgery within 1 year of diagnosis of colorectal cancer were included.
View Article and Find Full Text PDFSystematic literature review and meta-analysis of surgical treatment of complete rectal prolapse in male patients.
Tech Coloproctol
November 2024
Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Article Synopsis
- Rectal prolapse surgery outcomes were reviewed in predominantly male populations, examining factors like recurrence, complications, and bowel function.
- Eight studies involving 452 male patients showed that abdominal procedures had lower recurrence rates (6%) compared to perineal procedures (19.3%), but longer operative times.
- The best results for improving constipation and fecal incontinence were found after resection rectopexy and posterior mesh rectopexy, respectively.
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