One of the foundational principles of recent developments in evolutionary biology has been the acknowledgement of homeostasis as an organising principle of cellular development from unicellular origins. Fundamentally, this concerns the balance between the inside of a biological entity and its environment. Given that the organ of balance is the ear, and that the evolutionary provenance of the vestibular system can be traced back to fish, music provides a rich foundation for evolutionary biological inquiry. This paper considers a specific dimensional relationship in sonic experience between noise, signal, redundancy and anticipation. Drawing on the physics of Bohm and more recent developments in Rowlands's nilpotent quantum mechanics, I argue that the relationship between these four parameters is not only that they represent aspects of sonic experience, but that they are dimensionally distinct, where noise can be considered to be scalar, a signal (or a note) is a vector (having magnitude and direction), redundancy is bi-vectorial (involving degrees of repetition of signals over time), and anticipation is tri-vectorial (involving reflexive consideration of different orders of redundancy). In outlining the dimensional distinction between these variables, an analysis is presented which considers the relationship between the Shannon entropy of different dimensions in music. This shows that the entropy of noise has a particular bearing on the entropy of the other dimensions. This dimensional relation is also reflected in biological evidence, where Torday has shown there to be a direct correlation between the effect of gravitational "noise" on cellular communication, and by extension the evolution of consciousness.
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http://dx.doi.org/10.1016/j.pbiomolbio.2023.11.006 | DOI Listing |
J Clin Med
November 2024
Oral Pathology, Medicine and Radiology, Indiana University School of Dentistry, Indianapolis, IN 46202, USA.
JAMA Dermatol
January 2025
Department of Dermatology, University of California, San Francisco.
Cureus
October 2024
Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, USA.
Australas J Dermatol
December 2024
Department of Dermatology, Westmead Hospital, Westmead, New South Wales, Australia.
Background: Basal cell carcinomas (BCCs) are the most common cancers worldwide. Although most BCCs are amenable to local treatment, there are limited therapeutic options for surgically unresectable locally advanced and metastatic BCCs. Activation of the sonic hedgehog signalling pathway plays a significant role in the development of most BCCs.
View Article and Find Full Text PDFMol Biol Rep
October 2024
Department of Biochemistry & Microbiology, North South University, Dhaka, 1229, Bangladesh.
Glioblastoma Multiforme (GBM), designated as grade IV by the World Health Organization, is the most aggressive and challenging brain tumor within the central nervous system. Around 80% of GBM patients have a poor prognosis, with a median survival of 12-15 months. Approximately 90% of GBM cases originate from normal glial cells via oncogenic processes, while the remainder arise from low-grade tumors.
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