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Efficacy of an Autologous Dermal Fibroblast Injection in Reducing the Retear Rate After Arthroscopic Rotator Cuff Repair: A Prospective Randomized Controlled Trial.
Am J Sports Med
January 2025
Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
Background: Interest in biological augmentation for improving bone-tendon interface (BTI) healing after arthroscopic rotator cuff repair (ARCR) is growing. Dermal fibroblasts, known for collagen synthesis similar to tenocytes, have shown effectiveness in BTI healing in chronic rotator cuff tear (RCT) models in rabbits. However, no human clinical trials have been conducted.
View Article and Find Full Text PDFElectrospun robust, biodegradable, bioactive, and nanostructured sutures to accelerate the chronic wound healing.
Biofabrication
January 2025
College of Textiles & Clothing, Qingdao University, 308 Ningxia Road, Qingdao, Qingdao, Shandong, 266071, CHINA.
The design and development of advanced surgical sutures with appropriate structure and abundant bio-functions are urgently required for the chronic wound closure and treatment. In this study, an integrated technique routine combining modified electrospinning with hot stretching process was proposed and implemented to fabricate poly(L-lactic acid) (PLLA) nanofiber sutures, and the Salvia miltiorrhiza Bunge-Radix Puerariae herbal compound (SRHC) was encapsulated into PLLA nanofibers during the electrospinning process to enrich the biofunction of as-generated sutures. All the PLLA sutures loading without or with SRHC were found to exhibit bead-free and highly-aligned nanofiber structure.
View Article and Find Full Text PDFThread-Filler: A Standardized Combination Therapy.
J Craniofac Surg
January 2025
Department of Plastic, Reconstructive, and Aesthetic Surgery, Bilkay Clinic, Izmir, Turkey.
Advanced technology and increasing knowledge about aging faces have combined to create the illusion of thread lifting to replace surgical interventions. However, results that came far beyond expectations led to a heavy suspicion of these tools. However, combined treatments with fillers would have better outcomes with a synergetic effect.
View Article and Find Full Text PDFAutologous porcine VRAM flap model for VCA research.
Front Transplant
December 2024
Department of Surgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, United States.
Introduction: As research advances in vascularized composite allotransplantation (VCA), large animal models are essential for translational studies related to immune rejection and graft survival. However, procurement of large flaps can cause significant defects, complicating wound closure and increasing postoperative risks. This study details the surgical techniques and outcomes of autologous vertical rectus abdominis myocutaneous (VRAM) flap transplantation and neck flap isolation with induced ischemia in a swine model.
View Article and Find Full Text PDFExtended Superior Pedicle Autoaugmentation (ESPA) Mastopexy: A Review of 20 Consecutive Patients.
Aesthetic Plast Surg
December 2024
Postgraduate School of Plastic Surgery, University of Palermo, Palermo, Italy.
Background: Ptotic breast deformity arises from decreased breast tissue volume and skin laxity, causing descent of breast tissue due to gravity. Mastopexy lifts and reshapes the breast and can be potentially associated with breast implants in case of need of volume increase. However, this option is not accepted by all the patients.
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