AI Article Synopsis
- Rotavirus A is a virus that causes gastrointestinal diseases in many mammals, including humans and birds like chickens, but there is limited information on its impact on chicken populations in Japan.
- This study presents the first complete genome analysis of avian rotavirus A strains found in Japanese chickens, revealing specific genetic characteristics and their relationship to other strains.
- The genetic analysis indicates that the Japanese ARVA strains are genetically closer to Korean strains than to European ones, but more research is needed to understand their origins and relationships fully.
Article Abstract
Rotavirus A infects many mammalian species, including humans and causes diarrhea and gastrointestinal diseases. The virus also infects various bird species, including chickens, although information of avian rotavirus A (ARVA) infection in chicken populations in Japan is scarce. In this study, we report for the first time the whole-genome sequences of ARVA strains from Japanese chicken populations. The virus strains were inoculated to MA104 cells and cultured viruses were used to obtain the sequences with the MiSeq system, and genetic analysis demonstrated the genotype constellation of G19-P[30]-I11-R6-C6-M7-A16-N6-T8-E10-H8 of the Japanese chicken ARVA isolates. Phylogenetic analyses demonstrated that the VP1, VP2, VP3, VP4, VP7, NSP2, and NSP4 coding gene sequences of the Japanese strains were closer to those of Korean than the European ARVA strains, although such relationship was not clear for other genes. The data suggest that the Japanese ARVA strains and the ones in Korea have genetically close relationship, although the origin is not clear at this point. Further information including the whole-genome sequences of the Korean strains and sequences of other Japanese chicken ARVA strains will be necessary for elucidation of their origin.
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| http://dx.doi.org/10.1007/s11262-023-02040-9 | DOI Listing |
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First report of the whole-genome sequence analysis of avian rotavirus A from Japanese chickens.
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Laboratory of Veterinary Infectious Diseases, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo, 183-8509, Japan.
Article Synopsis
- Rotavirus A is a virus that causes gastrointestinal diseases in many mammals, including humans and birds like chickens, but there is limited information on its impact on chicken populations in Japan.
- This study presents the first complete genome analysis of avian rotavirus A strains found in Japanese chickens, revealing specific genetic characteristics and their relationship to other strains.
- The genetic analysis indicates that the Japanese ARVA strains are genetically closer to Korean strains than to European ones, but more research is needed to understand their origins and relationships fully.
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