Owing to high response rates, the Food and Drug Administration has approved both gene- and immune-targeted drugs for tumor-agnostic, genomic biomarker-based indications, for lethal solid and blood cancers. We posit that current data support tissue-agnostic activity as a paradigm, rather than an exception to the rule.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262846PMC
http://dx.doi.org/10.1038/s43018-023-00676-yDOI Listing

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