Deep learning models have been widely used during the last decade due to their outstanding learning and abstraction capacities. However, one of the main challenges any scientist has to face using deep learning models is to establish the network's architecture. Due to this difficulty, data scientists usually build over complex models and, as a result, most of them result computationally intensive and impose a large memory footprint, generating huge costs, contributing to climate change and hindering their use in computational-limited devices. In this paper, we propose a novel dense feed-forward neural network constructing method based on pruning and transfer learning. Its performance has been thoroughly assessed in classification and regression problems. Without any accuracy loss, our approach can compress the number of parameters by more than 70%. Even further, choosing the pruning parameter carefully, most of the refined models outperform original ones. Furthermore, we have verified that our method not only identifies a better network architecture but also facilitates knowledge transfer between the original and refined models. The results obtained show that our constructing method not only helps in the design of more efficient models but also more effective ones.
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http://dx.doi.org/10.1016/j.neunet.2023.12.015 | DOI Listing |
J Hazard Mater
December 2024
Discipline of Chemistry, The University of Newcastle, University Drive, Newcastle, New South Whales 2308, Australia; School of Chemistry, Monash University, Wellington Road, Melbourne, Victoria 3800, Australia. Electronic address:
Microplastics are ubiquitous and appear to be harmful, however, the full extent to which these inflict harm has not been fully elucidated. Analysing environmental sample data is challenging, as the complexity in real data makes both automated and manual analysis either unreliable or time-consuming. To address challenges, we explored a dense feed-forward neural network (DNN) for classifying Fourier transform infrared (FTIR) spectroscopic data.
View Article and Find Full Text PDFNat Commun
August 2024
School of Computer and Communication Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Communication by rare, binary spikes is a key factor for the energy efficiency of biological brains. However, it is harder to train biologically-inspired spiking neural networks than artificial neural networks. This is puzzling given that theoretical results provide exact mapping algorithms from artificial to spiking neural networks with time-to-first-spike coding.
View Article and Find Full Text PDFBrief Bioinform
May 2024
Division of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, MN 55455, United States.
Biomedical research now commonly integrates diverse data types or views from the same individuals to better understand the pathobiology of complex diseases, but the challenge lies in meaningfully integrating these diverse views. Existing methods often require the same type of data from all views (cross-sectional data only or longitudinal data only) or do not consider any class outcome in the integration method, which presents limitations. To overcome these limitations, we have developed a pipeline that harnesses the power of statistical and deep learning methods to integrate cross-sectional and longitudinal data from multiple sources.
View Article and Find Full Text PDFNat Commun
June 2024
Center for Molecular Medicine (CMM), University Medical Center Utrecht, Utrecht, The Netherlands.
Dense and aligned Collagen I fibers are associated with collective cancer invasion led by protrusive tumor cells, leader cells. In some breast tumors, a population of cancer cells (basal-like cells) maintain several epithelial characteristics and express the myoepithelial/basal cell marker Keratin 14 (K14). Emergence of leader cells and K14 expression are regarded as interconnected events triggered by Collagen I, however the underlying mechanisms remain unknown.
View Article and Find Full Text PDFThe posterior "tail" region of the striatum receives dense innervation from sensory brain regions and has been demonstrated to play a role in behaviors that require sensorimotor integration including discrimination , avoidance and defense responses. The output neurons of the striatum, the D1 and D2 striatal projection neurons (SPNs) that make up the direct and indirect pathways, respectively, are thought to play differential roles in these behavioral responses, although it remains unclear if or how these neurons display differential responsivity to sensory stimuli. Here, we used whole-cell recordings in vivo and ex vivo to examine the strength of excitatory and inhibitory synaptic inputs onto D1 and D2 SPNs following the stimulation of upstream auditory pathways.
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