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Systemic lupus erythematosus (SLE) associated uveitis in India - A case series. | LitMetric

Systemic lupus erythematosus (SLE) associated uveitis in India - A case series.

Indian J Ophthalmol

Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Published: May 2024

AI Article Synopsis

  • A study reports on the eye-related issues (uveitis) found in patients with systemic lupus erythematosus (SLE) over a six-year period.
  • Out of seven patients, predominantly female, the most common eye problem was retinal vasculitis, and many experienced bilateral symptoms.
  • Although SLE is uncommon in causing uveitis, proper diagnosis and treatment are crucial, as they can help preserve vision in affected individuals.

Article Abstract

Purpose: To report the uveitic manifestations of patients with systemic lupus erythematosus (SLE).

Methods: This was a retrospective analysis of all SLE cases with ocular manifestations seen by a single ophthalmologist between 2015 and December 2021.

Results: In total, seven patients with a median age of 40 (range 18-50) years were included in the study. Female (85.7%) predominance was noted. Ocular findings were bilateral in 71% (five patients) of cases. Majority (10 eyes, 83%) of the patients had retinal vasculitis as the common finding. Antinuclear antibodies were positive in all the patients. The vision improved in two (16.6%) eyes, was stable in eight (66%) eyes, and worsened in one (8%) eye. All the patients were treated with oral steroids along with immunosuppressive agents.

Conclusion: Though SLE is rare cause of uveitis, it can be associated with significant ocular morbidity. Hence, early diagnosis and treatment can salvage vision in many cases.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168564PMC
http://dx.doi.org/10.4103/IJO.IJO_1579_23DOI Listing

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