The downstream biosynthetic route of camptothecin has remained unclear for more than half a century. Here, we discovered a P450 enzyme involved in camptothecin biosynthesis from plant by chemoproteomics, which lays the foundation for synthesis of camptothecin and highlights the effectiveness of chemoproteomic profiling for discovering unknown enzymes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jipb.13594 | DOI Listing |
Publication Analysis
Top Keywords
chemoproteomics reveals
4
reveals epoxidase
4
epoxidase enzyme
4
enzyme biosynthesis
4
camptothecin
4
biosynthesis camptothecin
4
camptothecin ophiorrhiza
4
ophiorrhiza pumila
4
pumila downstream
4
downstream biosynthetic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!