Ampicillin-Sulbactam-Induced Liver Injury in a Pediatric Patient.

J Pediatr Pharmacol Ther

Department of Pharmacy (CF, KN), Johns Hopkins All Children's Hospital, St. Petersburg, FL.

Published: December 2023

Drug-induced liver injury (DILI) is a rare adverse drug reaction (ADR) in pediatric patients and limited reports exist examining ampicillin-sulbactam-induced liver injury. This report summarizes a 12-year-old male who received ampicillin-sulbactam and subsequently developed liver injury characterized by elevated serum aminotransferases and bilirubin. Ampicillin-sulbactam was subsequently discontinued and the patient's liver function tests (LFTs) rapidly improved. This report describes the rare adverse reaction of ampicillin-sulbactam-induced liver injury.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10715387PMC
http://dx.doi.org/10.5863/1551-6776-28.8.747DOI Listing

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