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Sex-biased gut dopamine signaling in multiple sclerosis. | LitMetric
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Sex-biased gut dopamine signaling in multiple sclerosis.

Shui Yu Melody Y Zeng

Immunity

Gale and Ira Drukier Institute for Children's Health, Weill Cornell Medicine, New York, NY 10065, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY 10065, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School, New York, NY 10065, USA. Electronic address:

Published: December 2023

Multiple sclerosis shows a strong sex bias, with unclear mechanisms. In this issue of Immunity, Peng et al. elucidate a female-biased increase in intestinal dopamine signaling that diminishes protective Lactobacillus and exacerbates inflammation in a mouse model of multiple sclerosis.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10908588PMC
http://dx.doi.org/10.1016/j.immuni.2023.11.016DOI Listing

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