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Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors. | LitMetric

Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors.

Curr Treat Options Oncol

Emory Winship Cancer Institute, 1365 Clifton Rd NE, Atlanta, GA, C5084 30322, USA.

Published: December 2023

AI Article Synopsis

  • Attempting a gross total resection of newly diagnosed suspected glioblastoma is preferred when it's safe, even for elderly patients and those with butterfly gliomas.
  • In cases where patients may not tolerate surgery well or the tumors are located in critical brain areas, a subtotal resection or biopsy might be more appropriate.
  • There's ongoing research into "supramaximal surgery," but currently, there's not enough evidence to make clear recommendations for this approach in specific cases.

Article Abstract

We have level II evidence that attempting a gross total resection of newly diagnosed suspected glioblastoma is preferred when a maximally safe resection can be attempted. This recommendation extends to elderly patients and those with butterfly gliomas. However, in cases where patients are poor surgical candidates, or for lesions in eloquent areas, subtotal resection or biopsy may be indicated. Recent studies have discussed "supramaximal surgery," which is defined in different ways by different teams, but there is not enough evidence, yet, to make a consistent recommendation for supramaximal resection for specific patients.

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Source
http://dx.doi.org/10.1007/s11864-023-01158-0DOI Listing

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