The review summarizes the published data on identification of biologically active compounds (BACs) and the pharmacological potential of various components of oleo-gum resin from the Indian frankincense Boswellia serrata Roxb. ex Colebr. Boswellia oleo-gum resin contains a wide range of BACs from the classes of mono-, sesqui-, di-, and triterpenes. Numerous in vivo and in vitro studies demonstrated their anti-inflammatory and antiproliferative effects. Boswellic acids (BAs), which belong to the tetra- and pentacyclic triterpenoid classes, showed the highest anti-inflammatory activity. The frankincense resin is traditionally used in Ayurvedic and Unani medicine and can provide a promising source to design drugs effective in treating musculoskeletal disorders.
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http://dx.doi.org/10.1134/S0012496623700643 | DOI Listing |
Toxicol Rep
June 2025
Food Toxicology & Contaminants Dept., National Research Centre, Dokki, Cairo, Egypt.
Cadmium (Cd) is among the most ecologically harmful heavy metals. The purpose of this work was to identify the biologically active components in dried oleo-resin-gum of extract (FAE) and assess their preventive efficacy against oxidative damage caused by Cd in rats. The biologically active components were identified using HPLC and GC-MS.
View Article and Find Full Text PDFFood Sci Nutr
December 2024
BC Food and Beverage Innovation Centre, Faculty of Land and Food Systems The University of British Columbia Vancouver British Columbia Canada.
Myrrh oleo-gum-resin (MOGR) is a natural substance that has a rich history of medicinal use due to its anti-inflammatory, antimicrobial, and antioxidant properties. The present study reports on the fabrication and assessment of pectin and K-carrageenan composite films infused with varying proportions (0.3%, 0.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Background: A growing body of research is dedicated to developing new therapeutic agents for wound healing with fewer adverse effects. One of the proceedings being taken today in wound healing research is to identify promising biological materials that not only heal wounds but also vanish scarring. The effectiveness of nanofibers like polyvinyl alcohol (PVA), in improving wound healing can be related to their unique properties.
View Article and Find Full Text PDFSci Rep
October 2024
Food Safety and Food Toxicology Lab, Department of Applied Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Pistacia lentiscus L. is an aromatic plant containing a significant percentage of essential oil (EO) used in fragrance, pharmaceuticals, cosmetics, and the food industry. The purpose of this work is focused on the optimization of Pistacia lentiscus L.
View Article and Find Full Text PDFPharmaceutics
September 2024
Department of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany.
Carboplatin (Cp) is a potent chemotherapeutic agent, but its effectiveness is constrained by its associated side effects. Frankincense, an oleo-gum resin from the tree, has demonstrated cytotoxic activity against cancer cells. This study explored the synergistic potential of nanoparticles formulated from methanolic extract (BME), to enhance the therapeutic efficacy of Cp at reduced doses.
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