Symptom-correlated MiRNA signature as a potential biomarker for Kawasaki disease.

Biomed J

Kawasaki Disease Center and Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

Published: October 2024

AI Article Synopsis

  • * These miRNAs play a role in co-regulating TGF-β signaling, which is implicated in the development of KD.
  • * The identified miRNA pattern could serve as a useful tool for objectively assessing the risk of developing KD.

Article Abstract

• The expression levels of ten miRNAs are highly correlated with KD. • These miRNAs can co-regulate TGF-β signaling involved in KD pathogenesis. • This symptom-correlated miRNA signature can provide an objective score for KD risk assessment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11399622PMC
http://dx.doi.org/10.1016/j.bj.2023.100684DOI Listing

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Symptom-correlated MiRNA signature as a potential biomarker for Kawasaki disease.

Biomed J

October 2024

Kawasaki Disease Center and Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Electronic address:

Article Synopsis
  • * These miRNAs play a role in co-regulating TGF-β signaling, which is implicated in the development of KD.
  • * The identified miRNA pattern could serve as a useful tool for objectively assessing the risk of developing KD.
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