The history of studies of melatonin effects on cancer in mice is outlined, the main lesson being that the systemic effects of melatonin on animals may overwhelm the effects found using tissue explants or cell cultures. In particular, the timing of melatonin administration is of crucial importance for using the drug, which is freely available over counter and thus needs no licensing for its applications in oncology.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10715041 | PMC |
| http://dx.doi.org/10.18632/oncotarget.28537 | DOI Listing |
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