Antifungal susceptibility profile and local epidemiological cut-off values of () : an emergent and rare opportunistic yeast.

, also known as , is an emerging opportunistic "rare pathogenic yeast". Due to the limited data on its antifungal susceptibility, the clinical treatments become challenging. Based on the China Hospital Invasive Fungal Surveillance Network (2009-2022), we conducted a comprehensive multi-method study on clinical isolates from various central hospitals. This study is currently the largest study carried out to assess the antifungal susceptibility of . It is also the first to establish local epidemiological cut-off values (L-ECOFFs), identify its mutations, and assess the consistency between the three prevalent commercial antifungal susceptibility testing methods and the broth microdilution method. We recommend the Sensititre YeastOne as the best option for antifungal susceptibility testing for , followed by the ATB FUNGUS 3. Nevertheless, practitioners should use the MIC test strip with discretion.