AI Article Synopsis
- * An analysis of 152 patients showed that a higher DLR is linked to increased mortality risk, with 20 patients dying within 30 days of monitoring.
- * The DLR proved to be an independent predictor of 30-day mortality, showing similar prognostic value as the MELD score, but the combination of both scores offered even better predictive accuracy.
Article Abstract
Background: HBV-associated decompensated cirrhosis (HBV-DC) is hallmarked by high short-term mortality. Accurate non-invasive prognostic tools for these patients are urgent clinical need. Thus, we aimed to explore the relationship between the plasma D-dimer to lymphocyte ratio (DLR) and mortality in HBV-DC patients.
Methods: A retrospective analysis was conducted on 152 patients with HBV-DC. To estimate disease severity and outcomes, the Model for End-Stage Liver Disease (MELD) score was utilized. The predictive value of the DLR in assessing mortality risk was assessed using multivariate logistic regression analysis and receiver operating characteristic curve analysis.
Results: During the 30-day follow-up period, 20 patients died. The DLR was markedly different between non-survivors and survivors and higher DLR was found to be linked with adverse consequences. Furthermore, logistic regression demonstrated DLR as an independent predictive factor of 30-day mortality in HBV-DC patients and the prognostic value of DLR was very similar to that of MELD score, the combinations of DLR and MELD score show a better predictive value than that of a single index.
Conclusions: The DLR was a reliable tool to predict 30-day mortality in HBV-DC patients.
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| http://dx.doi.org/10.7754/Clin.Lab.2023.230536 | DOI Listing |
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View Article and Find Full Text PDFArticle Synopsis
- * An analysis of 152 patients showed that a higher DLR is linked to increased mortality risk, with 20 patients dying within 30 days of monitoring.
- * The DLR proved to be an independent predictor of 30-day mortality, showing similar prognostic value as the MELD score, but the combination of both scores offered even better predictive accuracy.
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Methods: This work recruited 263 HBV-DC patients admitted to our hospital from November 2020 through March 2022.
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