Interictal epileptiform discharges (IEDs) are intermittent electrophysiological events that occur in patients with epilepsy between seizures. Automated detection of IEDs helps clinician to identify cortical irritations and relations to seizure recurrence. It also reduces the necessity of visual inspection by physicians interpreting the EEG. This paper presents a novel deep learning-based approach that combines one-dimensional local binary pattern symbolization method with a regularized multi-head one-dimensional convolutional neural network to learn unique morphological patterns from different EEG sub-bands for IED detection. Experimentation using the Temple University Events corpus scalp EEG data shows promising performance, e.g. F1-score of 87.18%.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1109/EMBC40787.2023.10340735 | DOI Listing |
Ann Neurol
January 2025
Department of Neurology, Comprehensive Epilepsy Center, Johns Hopkins University, Baltimore, MD, USA.
Objective: Whereas a scalp electroencephalogram (EEG) is important for diagnosing epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of routine EEGs show interictal epileptiform discharges (IEDs) and overall misdiagnosis rates of epilepsy are 20% to 30%. We aim to demonstrate how network properties in EEG recordings can be used to improve the speed and accuracy differentiating epilepsy from mimics, such as functional seizures - even in the absence of IEDs.
View Article and Find Full Text PDFEpilepsia
January 2025
Department of Medical Sciences, Institute of Neurology, Magna Græcia University, Catanzaro, Italy.
We aim to understand whether tremor may be an intrinsic feature of juvenile myoclonic epilepsy (JME) and whether individuals with JME plus tremor experience a different disease course. Thirty-one individuals with JME plus tremor (17 females, mean age = 33.9 ± 13.
View Article and Find Full Text PDFEpilepsia
January 2025
Department of Neuropediatrics and Muscular Disorders, Medical Center, Faculty of Medicine University of Freiburg, University of Freiburg, Freiburg im Breisgau, Germany.
Objective: Hypothalamic hamartomas (HHs) are associated with pharmacoresistant epilepsy. Stereotactic radiofrequency thermocoagulation (SRT) shows promise as a disconnecting intervention. Although magnetic resonance imaging (MRI) is typically used to determine the attachment and intervention side, it presents challenges in cases of bilaterally attached HH, where the epileptogenic side is unclear.
View Article and Find Full Text PDFBrain Dev
January 2025
Department of Clinical Neuroelectrophysiology, Wuhan Children's Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
Objective: There are fewer reports on the ictal electroencephalogram(EEG) of convulsions in infants and children with mild gastroenteritis (BCWG). Our study retrospectively analyzed the ictal EEG characteristics of convulsive episodes of BCWG.
Methods: The seizure-phase EEGs of children diagnosed with BCWG from September 2016 to January 2022 were searched and analyzed, and a total of thirteen seizure-phase EEGs of eight cases were analyzed retrospectively.
Medication refractory focal epilepsy creates a significant challenge, with approximately 30% of patients ineligible for surgery due to the involvement of eloquent cortex in the epileptogenic network. For such patients with limited surgical options, electrical neuromodulation represents a promising alternative therapy. In this study, we investigate the potential of non-invasive temporal interference (TI) electrical stimulation to reduce epileptic biomarkers in patients with epilepsy by comparing intracerebral recordings obtained before, during, and after TI stimulation, to recordings during low and high kHz frequency (HF) sham stimulation.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!