Implementation of multinuclear MRI/S as a diagnostic tool in clinical settings faces many challenges. One of those challenges is the development of highly sensitive multinuclear RF coils. Current multi-tuning techniques incorporate lossy components that impact the highest achievable SNR for at least one of the coil frequencies. As a result, optimization of multinuclear coil designs continues to be a priority for RF hardware engineers. To address this challenge, a new frequency switching technology that incorporates stimuli-responsive polymer materials was explored. Q measurements were used as a comparison metric between single-tuned, a standard switching network, and the proposed switching technology. The Q losses measured in the new switching method remained below 38% when compared to single-tuned coils. These results are consistent with low loss values reported using traditional switching networks. Furthermore, preliminary testing indicates that there is potential for improvement. These results establish the new technology as a promising alternative to traditional switching techniques.Clinical Relevance- A low loss multi-tuning technique for MRI radiofrequency coils has the potential of improving the study and diagnosis of disease.
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http://dx.doi.org/10.1109/EMBC40787.2023.10340712 | DOI Listing |
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
Implementation of multinuclear MRI/S as a diagnostic tool in clinical settings faces many challenges. One of those challenges is the development of highly sensitive multinuclear RF coils. Current multi-tuning techniques incorporate lossy components that impact the highest achievable SNR for at least one of the coil frequencies.
View Article and Find Full Text PDFMagn Reson Med
November 2023
Department of Electrical and Computer Engineering, Texas A&M University, College Station, Texas, USA.
Purpose: Multinuclear MRI/S is of increasing interest. Currently, most multinuclear receive array coils are constructed by nesting multiple single-tuned array coils or using switching elements to control the operating frequency, in which case more than one set of conventional isolation preamplifiers and associated decoupling circuits is required. These conventional configurations rapidly become complicated when greater numbers of channels or nuclei are needed.
View Article and Find Full Text PDFTransl Stroke Res
August 2023
The National High Magnetic Field Laboratory, Florida State University, 1800 E. Paul Dirac Dr, Tallahassee, FL, 32310, USA.
Compromised adult human mesenchymal stem cells (hMSC) can impair cell therapy efficacy and further reverse ischemic recovery. However, in vitro assays require extended passage to characterize cells, limiting rapid assessment for therapeutic potency. Multinuclear magnetic resonance imaging and spectroscopy (MRI/S) provides near real-time feedback on disease progression and tissue recovery.
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