Data from 80 high-risk low birth infants were analysed to determine whether there is a clinical association between Retinopathy of Prematurity (ROP) and Peri-Intraventricular Hemorrhages (PIVH) in preterm newborns. Diagnosis of retinopathy was made by retinal examination at approximately four weeks of age. All infants were routinely and repeatedly scanned by real-time ultrasound to diagnose the presence of Peri-Intraventricular Hemorrhages. PIVH was clearly present in 41 (51.2%) of them, whereas 39 (48.7%) infants had no evidence of intracerebral bleeding. We found no statistically significant association between cicatricial retinopathy and PIVH (P = 0.1). We suppose therefore, that the sensitivity of retinal vasculature and cerebral vasculature to the various factors considered to be important in the development of PIVH is different.
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http://dx.doi.org/10.1055/s-2008-1052527 | DOI Listing |
Front Pediatr
February 2025
Department of Neonatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Background: With advances in perinatal medicine, there has been a rise in the preterm birth rate, especially the rate of very low birth weight (VLBW) and extremely low birth weight infants. Studies have shown that maternal age during pregnancy and at the time of delivery is associated with pregnancy complications and poor neonatal outcomes. Little is known about the effect of maternal age on the outcome of very low birth weight infants.
View Article and Find Full Text PDFDiagnostics (Basel)
February 2025
Department of Pediatrics, Nagoya City University West Medical Center, Nagoya 462-8505, Japan.
: Retinopathy of prematurity (ROP) is a serious disease causing blindness in childhood. Gestational age (GA) and birth weight are major factors associated with the development and progression of ROP, but postnatal systemic inflammation is also an important well-known risk factor. : This study retrospectively analyzed the relationship between systemic inflammation and ROP severity using the corrected GA (CGA), which reflects the intrinsic immaturity of the infant, rather than days of life.
View Article and Find Full Text PDFBMC Ophthalmol
March 2025
Department of Ophthalmology, Kastamonu University, Kastamonu, Turkey.
Background: This study aimed to investigate the long-term effects of retinopathy of prematurity (ROP) on visual function and ocular anatomy. We compared biometric values, foveal thickness, and choroidal thickness among children with a history of ROP (stratified by treatment status), premature infants without ROP, and term-born children.
Methods: This cross-sectional study was conducted between september 2021 and february 2022 at the Ophthalmology Department of Ankara Bilkent City Hospital.
Pediatr Res
March 2025
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: This study was designed (1) to compare growth, morbidity and mortality in < 33-week gestational age (GA) (very preterm, VPT) or very low birth weight (BW < 1500 grams, VLBW) infants before (Epoch-1) and after implementing routine enteral zinc (Zn) supplementation (Epoch-2) to meet recommendations, and (2) to assess serum Zn levels and associated variables.
Methods: Single-center prospective cohort of 826 infants. The primary outcome was the change (Δ) in Z-scores of accurate length (Δlength), weight and head circumference from birth to discharge home.
Med Hypothesis Discov Innov Ophthalmol
February 2025
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. It predominantly affects preterm infants with very low birth weights or extreme prematurity. Aberrant retinal vascular development, driven by hyperoxia and hypoxia-induced neovascularization, is central to ROP pathogenesis.
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