Hepatitis C infection and HIV/AIDS contaminations are normal in certain areas of the world, and because of their geographic overlap, co-infection can't be precluded as the two illnesses have a similar transmission course. This current work presents a co-infection model of HIV/AIDS and Hepatitis C virus with fuzzy parameters. The application of fuzzy theory aids in tackling the issues associated with measuring uncertainty in the mathematical depiction of diseases. The fuzzy reproduction number and fuzzy equilibrium points have been determined in this context, focusing on a model applicable to a specific group defined by a triangular membership function. Furthermore, for the model, a fuzzy non-standard finite difference (NSFD) technique has been developed, and its convergence is examined within a fuzzy framework. The suggested model is numerically validated, confirming the dependability of the devised NSFD technique, which successfully retains all of the key properties of a continuous dynamical system.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10713727 | PMC |
| http://dx.doi.org/10.1038/s41598-023-48085-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical and microbiological characteristics and prognosis of invasive infection caused by in the community.
Ann Med
December 2025
Critical care department, Zhongshan City People's Hospital, Guangdong Province, China.
Background: The incidence of invasive infection of (Kp) in the community is increasing every year, and the high disability and mortality rates associated with them pose great challenges in clinical practice. This study aimed to explore the clinical and microbiological characteristics of Kp invasive infection in the community.
Method: This study investigated the data of 291 patients with Kp infection in the community in three hospitals (Zhongshan City, Guangdong Province) from January 2020 to August 2023.
Expert consensus on the benefits of neuraminidase in conventional influenza vaccines: a Delphi study.
BMC Infect Dis
January 2025
Patient-Centered Research, Evidera, London, UK.
Background: Seasonal vaccination is the mainstay of human influenza prevention. Licensed influenza vaccines are regularly updated to account for viral mutations and antigenic drift and are standardised for their haemagglutinin content. However, vaccine effectiveness remains suboptimal.
View Article and Find Full Text PDFCo-infection of nervous necrosis virus and Vibrio harveyi increased mortality and worsened the disease severity in the orange-spotted grouper (Epinephelus coioides).
Fish Shellfish Immunol
January 2025
College of Marine Sciences, South China Agricultural University, Guangzhou, 510642, China; Nansha-South China Agricultural University Fishery Research Institute, Guangzhou, 511464, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Electronic address:
Co-infections of different pathogenic microorganisms usually cause complex effects, and receive more attention. Red-grouper nervous necrosis virus (RGNNV) and Vibrio are the common viral and bacterial pathogens of fish, and are often detected simultaneously in diseased fish. However, the understanding of co-infection of RGNNV and Vibrio is still unclear.
View Article and Find Full Text PDFRecombinant collagen microneedles for transdermal delivery of antibacterial copper-DNA nanoparticles to treat skin and soft tissue infections.
J Control Release
January 2025
School of Pharmacy, Changzhou University, Changzhou 213164, China; School of Medical and Health Engineering, Changzhou University, Changzhou 213164, PR China. Electronic address:
Skin and soft tissue infections (SSTI) include bacterial infections of the skin, muscles, and connective tissue such as ligaments and tendons. SSTI in patients with immunocompromising diseases may lead to chronic, hard-to-heal infected wounds, resulting in disability, amputation, or even death. To treat SSTI and rebuild the defensive barrier of the skin, here we utilize recombinant type XVII collagen protein (rCol XVII) to construct biodegradable, regenerative collagen microneedles (rCol-MN) for transdermal delivery of antibacterial agents.
View Article and Find Full Text PDFDevelopment and validation of a high-throughput qPCR platform for the detection of soil-transmitted helminth infections.
PLoS Negl Trop Dis
January 2025
DeWorm3 Project, Seattle, Washington, United States of America.
Background: Historically, soil-transmitted helminth (STH) control and prevention strategies have relied on mass drug administration efforts targeting preschool and school-aged children. While these efforts have succeeded in reducing morbidity associated with STH infection, recent modeling efforts have suggested that expanding intervention to treatment of the entire community could achieve transmission interruption in some settings. Testing the feasibility of such an approach requires large-scale clinical trials, such as the DeWorm3 cluster randomized trial.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!