This article is the written account of a discussion between a group of indigenous women (trained both in Western and Indigenous knowledge systems), on the relevance of diagnosis in their conceptualisations of health and illness.
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Sociol Health Illn
March 2024
Te Kura Tātai Hauora, School of Health, Te Herenga Waka-Victoria University of Wellington, Wellington, New Zealand.
This article is the written account of a discussion between a group of indigenous women (trained both in Western and Indigenous knowledge systems), on the relevance of diagnosis in their conceptualisations of health and illness.
View Article and Find Full Text PDFA spatiotemporal optimization method for nutrient control in lake watersheds.
J Environ Manage
January 2024
Institute of Strategic Planning, Chinese Academy of Environmental Planning, Beijing, 100041, PR China; College of Environment, Liaoning University, Shenyang, 110036, PR China. Electronic address:
Developing an efficient strategy for managing nutrients in less-developed lake watersheds that can balance the need for socioeconomic progress with the protection of aquatic ecosystems has become an urgent research subject for achieving sustainable development. This paper improves the optimization method for environmental and economic management of lake watersheds proposed in our previous research. A spatiotemporal optimization method based on a coupling model consisting of the Soil and Water Assessment Tool, system dynamics model, and objective programming model was applied to an agricultural non-point source (ANPS) pollution control program and a rural sewage treatment program at the Yilong Lake watershed as a case study.
View Article and Find Full Text PDFThe potential role of FNDC5/irisin in various liver diseases: awakening the sleeping beauties.
Expert Rev Mol Med
June 2022
Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Fibronectin type III domain-containing protein 5 (FNDC5) is a transmembrane protein and the precursor of irisin, which serves as a systemic exerkine/myokine with multiple origins. Since its discovery in 2012, this hormone-like polypeptide has rapidly evolved to a component significantly involved in a gamut of metabolic dysregulations and various liver diseases. After a decade of extensive investigation on FNDC5/irisin, we are still surrounded by lots of open questions regarding its diagnostic and therapeutic values.
View Article and Find Full Text PDFRecent Advances in Isolation, Synthesis and Biological Evaluation of Terrein.
Chem Biodivers
December 2021
Key Laboratory of Tropical Medicinal Resources Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, 571158, P. R. China.
Terrein is a small-molecule polyketide compound with a simple structure mainly isolated from fungi. Since its discovery in 1935, many scholars have conducted a series of research on its structure identification, isolation source, production increase, synthesis and biological activity. Studies have shown that terrein has a variety of biological activities, not only can inhibit melanin production and epidermal hyperplasia, but also has anti-cancer, anti-inflammatory, anti-angiopoietic secretion, antibacterial, insecticidal activities, and so on.
View Article and Find Full Text PDFIntegrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats.
Front Genet
January 2020
Key Laboratory of Animal (Poultry) Genetics Breeding and Reproduction, Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
The Zhongwei goat is kept primarily for its beautiful white, curly pelt that appears when the kid is approximately 1 month old; however, this representative phenotype often changes to a less curly phenotype during postnatal development in a process that may be mediated by multiple molecular signals. DNA methylation plays important roles in mammalian cellular processes and is essential for the initiation of hair follicle (HF) development. Here, we sought to investigate the effects of genome-wide DNA methylation by combining expression profiles of the underlying curly fleece dynamics.
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