The rapid development of large language models has significantly reduced the cost of producing rumors, which brings a tremendous challenge to the authenticity of content on social media. Therefore, it has become crucially important to identify and detect rumors. Existing deep learning methods usually require a large amount of labeled data, which leads to poor robustness in dealing with different types of rumor events. In addition, they neglect to fully utilize the structural information of rumors, resulting in a need to improve their identification and detection performance. In this article, we propose a new rumor detection framework based on bi-directional multi-level graph contrastive learning, BiMGCL, which models each rumor propagation structure as bi-directional graphs and performs self-supervised contrastive learning based on node-level and graph-level instances. In particular, BiMGCL models the structure of each rumor event with fine-grained bidirectional graphs that effectively consider the bi-directional structural characteristics of rumor propagation and dispersion. Moreover, BiMGCL designs three types of interpretable bi-directional graph data augmentation strategies and adopts both node-level and graph-level contrastive learning to capture the propagation characteristics of rumor events. Experimental results on real datasets demonstrate that our proposed BiMGCL achieves superior detection performance compared against the state-of-the-art rumor detection methods.
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http://dx.doi.org/10.7717/peerj-cs.1659 | DOI Listing |
BMC Med Res Methodol
January 2025
School of Management, Beijing University of Chinese Medicine, Beijing, China.
Purpose: The process of searching for and selecting clinical evidence for systematic reviews (SRs) or clinical guidelines is essential for researchers in Traditional Chinese medicine (TCM). However, this process is often time-consuming and resource-intensive. In this study, we introduce a novel precision-preferred comprehensive information extraction and selection procedure to enhance both the efficiency and accuracy of evidence selection for TCM practitioners.
View Article and Find Full Text PDFCell Mol Biol Lett
January 2025
PhD Program in Medical Neuroscience, Taipei Medical University, Taipei, Taiwan (R.O.C.).
Background: Regulation of messenger RNA (mRNA) transport and translation in neurons is essential for dendritic plasticity and learning/memory development. The trafficking of mRNAs along the hippocampal neuron dendrites remains translationally silent until they are selectively transported into the spines upon glutamate-induced receptor activation. However, the molecular mechanism(s) behind the spine entry of dendritic mRNAs under metabotropic glutamate receptor (mGluR)-mediated neuroactivation and long-term depression (LTD) as well as the fate of these mRNAs inside the spines are still elusive.
View Article and Find Full Text PDFMol Imaging Biol
January 2025
Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Purpose: We aim to perform radiogenomic profiling of breast cancer tumors using dynamic contrast magnetic resonance imaging (MRI) for the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) genes.
Methods: The dataset used in the current study consists of imaging data of 922 biopsy-confirmed invasive breast cancer patients with ER, PR, and HER2 gene mutation status. Breast MR images, including a T1-weighted pre-contrast sequence and three post-contrast sequences, were enrolled for analysis.
Nat Commun
January 2025
The Medical Image and Health Informatics Lab, the School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Despite vast data support in DNA methylation (DNAm) biomarker discovery to facilitate health-care research, this field faces huge resource barriers due to preliminary unreliable candidates and the consequent compensations using expensive experiments. The underlying challenges lie in the confounding factors, especially measurement noise and individual characteristics. To achieve reliable identification of a candidate pool for DNAm biomarker discovery, we propose a Causality-driven Deep Regularization framework to reinforce correlations that are suggestive of causality with disease.
View Article and Find Full Text PDFNeural Netw
January 2025
School of Computer Engineering and Science, Shanghai University, Shanghai, 200444, China. Electronic address:
Conditional adversarial domain adaptation (CADA) is one of the most commonly used unsupervised domain adaptation (UDA) methods. CADA introduces multimodal information to the adversarial learning process to align the distributions of the labeled source domain and unlabeled target domain with mode match. However, CADA provides wrong multimodal information for challenging target features due to utilizing classifier predictions as the multimodal information, leading to distribution mismatch and less robust domain-invariant features.
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