Two-year experience of radiotherapy combined with local hyperthermia, hyperglycemia and chemotherapeutic drugs in patients with tumors of the upper respiratory tract showed advantages of this method. The results were compared with those of the control group of patients on radiotherapy only. Three therapeutic schemes were employed. Hyperthermia was performed in 2 temperature regimens. Of chemotherapeutic drugs platidiam, methotrexate, 5-FU and vinblastine were used.
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Cureus
June 2024
Emergency Medicine, United Lincolnshire Hospitals NHS Trust, Boston, GBR.
Diabetic ketoacidosis (DKA) is an extreme complication of diabetes mellitus characterized by hyperglycemia, metabolic acidosis, and ketonemia. Thyroid storm, a potentially life-threatening manifestation of thyrotoxicosis, presents with a multitude of symptoms, including hyperthermia, tachycardia, and altered mental status. Periodic paralysis can be precipitated by different metabolic disturbances, including thyrotoxicosis, and may lead to extreme episodes of muscle weakness and paralysis.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2024
College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, P. R. China.
Commencing with the breakdown of the diabetic osteoimmune microenvironment, multiple pathogenic factors, including hyperglycemia, inflammation, hypoxia, and deleterious cytokines, are conjointly involved in the progression of diabetic periodontal bone regeneration. Based on the challenge of periodontal bone regeneration treatment and the absence of real-time feedback of blood oxygen fluctuation in diabetes mellitus, a novel self-adaptive hyperthermia supramolecular cascade nano-reactor ACFDG is constructed via one-step supramolecular self-assembly strategy to address multiple factors in diabetic periodontal bone regeneration. Hyperthermia supramolecular ACFDG possesses high photothermal conversion efficiency (32.
View Article and Find Full Text PDFAm J Physiol Endocrinol Metab
May 2024
Exercise Physiology Lab at Toledo, University of Castilla-La Mancha, Toledo, Spain.
We investigated if a bout of exercise in a hot environment (HEAT) would reduce the postprandial hyperglycemia induced by glucose ingestion. The hypothesis was that HEAT stimulating carbohydrate oxidation and glycogen use would increase the disposal of an ingested glucose load [i.e.
View Article and Find Full Text PDFFree Radic Biol Med
April 2024
Institute of Cell Biophysics of Russian Academy of Sciences, Institutskaya st., 3, Pushchino, 142290, Russia.
NADPH oxidase is a target of hyperglycemia in type 2 diabetes mellitus (T2DM), which causes dysregulation of enzyme. Alterations in regulation of NADPH oxidase activity mediated receptor and non-receptor signaling in bone marrow granulocytes of mice with obesity-induced T2DM were studied. The animals fed high fat diet (516 kcal/100 g) for 16 weeks.
View Article and Find Full Text PDFFront Vet Sci
January 2024
Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
A 14-year-old female domestic short-haired cat with a diagnosed diabetes mellitus and acromegaly was presented for lethargy and dysorexia. On clinical presentation, the patient showed hyperglycemia, hyperthermia, dull mentation, and dehydration. With the suspicion of an inflammatory or infectious complication of diabetes, she was hospitalized with constant rate infusion of insulin, and empirical ampicillin sulbactam was started.
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