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http://dx.doi.org/10.1089/heq.2023.0033 | DOI Listing |
Mol Biol Rep
January 2025
Equipe Biologie Moléculaire et Biotechnologies, Laboratoire de Recherche, Centre MURAZ, Institut National de Santé Publique, Bobo-Dioulasso, Burkina Faso.
Background: Wolbachia is an endosymbiont bacterium known to stimulate host immunity against arboviruses and protozoa. Côte d'Ivoire is in a malaria-endemic region, and has experienced several dengue epidemics in recent decades as well. In order to help reduce the transmission of pathogens by mosquito vectors, we studied the prevalence of Wolbachia and the distribution of Cytoplasmic incompatibility factors (Cif) genes in different mosquito species caught in the wild in Cote d'Ivoire.
View Article and Find Full Text PDFMed Oncol
January 2025
School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Gelugor, Penang, Malaysia.
Nasopharyngeal carcinoma (NPC) is a distinctive epithelial cancer closely associated with Epstein-Barr Virus (EBV) infection, posing significant challenges in diagnosis and treatment due to its resistance to conventional therapies and high recurrence rates. Current therapies, including radiotherapy and chemotherapy, exhibit limited efficacy, particularly in recurrent or metastatic cases, highlighting the urgent need for novel therapeutic strategies. Targeting EBV oncoproteins, such as Epstein-Barr Virus encoded Nuclear Antigen 1 (EBNA1), Latent Membrane Protein 1 (LMP1), and Latent Membrane Protein 2 (LMP2), presents a promising therapeutic avenue in NPC treatment.
View Article and Find Full Text PDFJ Gastroenterol
January 2025
School of Medicine, Anhui University of Science & Technology, Huainan, China.
Background: Liver cirrhosis represents a critical stage of chronic liver disease, characterized by progressive liver damage, cellular dysfunction, and disrupted cell-to-cell interactions. Glycosylation, an essential post-translational modification, significantly influences cellular behavior and disease progression. Its role in cirrhosis at the single-cell level remains unclear, despite its importance.
View Article and Find Full Text PDFTheor Appl Genet
January 2025
Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Anthocyanins not only serve as critical pigments determining floral hues but also play essential roles in attracting insects for pollination, feeding animals and mitigating abiotic stress. However, the molecular mechanisms underlying the regulation of flower color in sesame has not yet been reported. In this study, an F population was constructed by crossing 'Ganzhi 9' (purple-flowered) with 'BS377' (white-flowered).
View Article and Find Full Text PDFAcetyl-CoA is the main substrate of lipid metabolism and functions as an energy source for plant development. In the cytoplasm, acetyl-CoA is mainly produced by ATP-citrate lyase (ACL), which is composed of ACLA and ACLB subunits. In this study, we isolated the restorer-4 (res4) of the thermosensitive genic male sterile mutant reversible male sterile-2 (rvms-2) in Arabidopsis (Arabidopsis thaliana).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!