AI Article Synopsis
- Using liver phantoms that mimic human tissue is vital for clinical training, disease diagnosis, and treatment planning, as it helps simulate real liver functions.
- The materials used to create these phantoms need to match the mechanical properties of actual liver tissue, including aspects like viscosity and elasticity, for accurate study.
- This paper discusses the pros and cons of various materials for crafting these liver-mimicking phantoms, emphasizing their role in improving diagnostic quality and treatment effectiveness.
Article Abstract
Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar to those of the real liver organ in the human body. This tissue-equivalent material is essential for qualitative and quantitative investigation of the liver mechanisms in producing nutrients, excretion of waste metabolites, and tissue deformity at mechanical stimulus. This paper reviews the mechanical properties of human hepatic tissues to develop liver-mimicking phantoms. These properties include viscosity, elasticity, acoustic impedance, sound speed, and attenuation. The advantages and disadvantages of the most common fabrication materials for developing liver tissue-mimicking phantoms are also highlighted. Such phantoms will give a better insight into the real tissue damage during the disease progression and preservation for transplantation. The liver tissue-mimicking phantom will raise the quality assurance of patient diagnostic and treatment precision and offer a definitive clinical trial data collection.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963485 | PMC |
| http://dx.doi.org/10.1007/s10237-023-01785-4 | DOI Listing |
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