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The incidence of Popeye Deformity after Soft Tissue Biceps Tenodesis is Comparable to Biceps Anchor Tenodesis and Lower than Biceps Tenotomy During Arthroscopic Rotator Cuff Repair.
Arthroscopy
January 2025
Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:
Thank you for your deep interest in our article entitled "The incidence of Popeye Deformity after Soft Tissue Biceps Tenodesis is Comparable to Biceps Anchor Tenodesis and Lower than Biceps Tenotomy During Arthroscopic Rotator Cuff Repair". We'll do our best to answer your questions.
View Article and Find Full Text PDFReal-world use of tafasitamab preceding CD19-directed chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma.
Biomark Res
January 2025
Incyte Corporation, Wilmington, DE, USA.
Potential CD19 antigen loss following CD19-directed therapy has raised concerns over sequential use of these therapies. Tafasitamab, a CD19-targeting immunotherapy, combined with lenalidomide, is approved for relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL) treatment in adults ineligible for autologous stem cell transplantation. This retrospective analysis examined characteristics and outcomes of adults with R/R DLBCL who received tafasitamab preceding CD19-directed chimeric antigen receptor T-cell (CAR-T) therapy in a real-world setting.
View Article and Find Full Text PDFBehavioral nudges prevent loan delinquencies at scale: A 13-million-person field experiment.
Proc Natl Acad Sci U S A
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The Harris School of Public Policy, University of Chicago, Chicago, IL 60637.
Americans collectively hold over $1.6 trillion in student loan debt, and over the last decade millions of borrowers have defaulted on loans, with serious consequences for their financial health. In a 13-million-person field experiment with the U.
View Article and Find Full Text PDFPeer-review Blinded Assay Test (P-BAT): a framework for trustless laboratory quality assurance for state-regulated cannabis markets.
J Cannabis Res
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PureVita Labs LLC, 153 James P Murphy Ind Hwy , West Warwick, 02893-2382, United States.
The purpose of laboratory testing in the cannabis industry is to ensure public safety by preventing products that exceed hazardous limits of contaminants from reaching consumers, and to provide consumers with transparent and accurate label information so that they can make informed decisions when purchasing and using products. However, cannabis testing does not exist in a vacuum of incentives-some incentives exist that are in direct conflict with what is best for consumers. For example, cultivators and distributors will prefer to use the services of laboratories that find the highest THC concentrations or lowest contaminant concentrations, regardless of the accuracy of their testing results.
View Article and Find Full Text PDFOne size does not fit all: revising traditional paradigms for assessing accuracy of QSAR models used for virtual screening.
J Cheminform
January 2025
National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Rockville, MD, 20850, USA.
Traditional best practices for quantitative structure activity relationship (QSAR) modeling recommend dataset balancing and balanced accuracy (BA) as the key desired objective of model development. This study explores the value of the conventional norms in the context of using QSAR models for virtual screening of modern large and ultra-large chemical libraries. For this increasingly common task, we now recommend the use of models with the highest positive predictive value (PPV) built on imbalanced training sets as preferred virtual screening tools.
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