AI Article Synopsis
- - Histones are essential proteins that help package DNA into condensed structures called chromatin in eukaryotic cell nuclei, enabling access for DNA replication and transcription.
- - These proteins are dynamic, changing their structure and distribution to allow different gene regulatory processes, especially important for plants which need to adapt quickly to their environments.
- - The review discusses how histones and their variants contribute to gene regulation in plants, focusing on their roles, modifications, and how they are distributed across plant genomes.
Article Abstract
Histones are crucial proteins that are involved in packaging the DNA as condensed chromatin inside the eukaryotic cell nucleus. Rather than being static packaging units, these molecules undergo drastic variations spatially and temporally to facilitate accessibility of DNA to replication, transcription as well as wide range of gene regulatory machineries. In addition, incorporation of paralogous variants of canonical histones in the chromatin is ascribed to specific functions. Given the peculiar requirement of plants to rapidly modulate gene expression levels on account of their sessile nature, histones and their variants serve as additional layers of gene regulation. This review summarizes the mechanisms and implications of distribution, modifications and differential incorporation of histones and their variants across plant genomes, and outlines emerging themes.
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| http://dx.doi.org/10.1016/j.bbagen.2023.130539 | DOI Listing |
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