Biodegradable polymers are materials that, thanks to their remarkable properties, are widely understood to be suitable for use in scientific fields such as tissue engineering and materials engineering. Due to the alarming increase in the number of diagnosed diseases and conditions, polymers are of great interest in biomedical applications especially. The use of biodegradable polymers in biomedicine is constantly expanding. The application of new techniques or the improvement of existing ones makes it possible to produce materials with desired properties, such as mechanical strength, controlled degradation time and rate and antibacterial and antimicrobial properties. In addition, these materials can take virtually unlimited shapes as a result of appropriate design. This is additionally desirable when it is necessary to develop new structures that support or restore the proper functioning of systems in the body.
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http://dx.doi.org/10.3390/ijms242316952 | DOI Listing |
Pharmaceutics
December 2024
Department of Chemical Engineering, College of Engineering, University of Rhode Island, Kingston, RI 02881, USA.
Background: Resveratrol (RSV) is a natural polyphenol that offers antioxidant, anti-inflammatory, and chemopreventive benefits. This project determined the ability of RSV-loaded nanoparticles (NP) to inhibit the growth of lung tumor spheroids in vitro.
Methods: RSV was encapsulated in NP comprised of the biodegradable polymer, acetalated dextran.
Pharmaceutics
November 2024
Department of Cell Biology and Molecular Genetics, Sri Devraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar 563103, India.
Cancer, the most common condition worldwide, ranks second in terms of the number of human deaths, surpassing cardiovascular diseases. Uncontrolled cell multiplication and resistance to cell death are the traditional features of cancer. The myriad of treatment options include surgery, chemotherapy, radiotherapy, and immunotherapy to treat this disease.
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December 2024
Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania.
Blending poly(3-hydroxybutyrate) (PHB) with other polymers could be a rapid and accessible solution to overcome some of its drawbacks. In this work, PHB was modified with microfibrillated cellulose (MC) and a thermoplastic polyurethane containing biodegradable segments (PU) by two routes, using a masterbatch and by direct mixing. The PU and MC modifiers improved the thermal stability of PHB by up to 13 °C and slightly decreased its melt viscosity and crystallinity, thus improving the melt processability.
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December 2024
Department of Engineering, Pegaso Telematic University, 80143 Naples, Italy.
Lactic acid (LA) is a versatile, optically active compound with applications across the food, cosmetics, pharmaceutical, and chemical industries, largely driven by its role in producing biodegradable polylactic acid (PLA). Due to its abundance, lignocellulosic biomass is a promising and sustainable resource for LA production, although media derived from these matrices are often rich in xylose and contain growth inhibitors. This study investigates LA production using a xylose-rich medium derived from DC stalks treated through steam explosion and enzymatic hydrolysis.
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December 2024
Department of Technology and Entrepreneurship in Wood Industry, Institute of Wood Sciences and Furniture, Warsaw University of Life Sciences-SGGW, 159 Nowoursynowska St., 02-776 Warsaw, Poland.
This study investigates the properties of composites produced using post-consumer polypropylene (PP) reinforced with lignocellulosic fillers from (black cumin) and rapeseed pomace. Using agri-food by-products like pomace supports waste management efforts and reduces the demand for wood in wood-plastic composites. The composite production method combined extrusion and hot flat pressing.
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