In sporadic idiopathic pulmonary fibrosis (sIPF) and pulmonary fibrosis caused by a mutation in telomere (TRG-PF) or surfactant related genes (SRG-PF), there are a number of aberrant cellular processes known that can lead to fibrogenesis. We investigated whether RNA expression of genes involved in these processes differed between sIPF, TRG-PF, and SRG-PF and whether expression levels were associated with survival. RNA expression of 28 genes was measured in lung biopsies of 26 sIPF, 17 TRG-PF, and 6 SRG-PF patients. Significant differences in RNA expression of ( = 0.02) and ( = 0.02) were found between sIPF, TRG-PF, and SRG-PF. Patients with low (
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10706203 PMC http://dx.doi.org/10.3390/ijms242316748 DOI Listing Publication Analysis
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