Application of Metal-Based Catalysts for Semi-Hydrogenation of Alkynol: A Review.

Alkynol semi-hydrogenation plays a vital role in industrial processes, due to the significance of its main product, enol, in high-end chemical synthesis, such as medicine, pesticide, food additives, and polymer monomer synthesis. Multiple intermediates are formed through a complex series of parallel or continuous reactions under varying conditions. However, the selectivity and efficiency of catalysts for producing these products still pose significant challenges. This review aims to thoroughly discuss the challenges and advancements in catalysts using different species and supports under various reaction conditions. Furthermore, strategies to enhance the yield and rate of enols are summarized based on noble metals, non-noble metals, and metal comparisons. By addressing diverse catalysts and reaction conditions, this review provides valuable insights into improving the semi-hydrogenation of acetylenic alcohols to enols.