Breaking Barriers: AI's Influence on Pathology and Oncology in Resource-Scarce Medical Systems.

Cancers (Basel)

Department of Pathology, County Clinical Emergency Hospital, Faculty of Medicine and Pharmacy, University of Oradea, 1 December Sq. No. 10, 410087 Oradea, Romania.

Published: December 2023

The application of artificial intelligence to improve the access of cancer patients to high-quality medical care is one of the goals of modern medicine. Pathology constitutes the foundation of modern oncologic treatment, and its role has expanded far beyond diagnosis into predicting treatment response and overall survival. However, the funding of pathology is often an afterthought in resource-scarce medical systems. The increased digitalization of pathology has paved the way towards the potential use of artificial intelligence tools for improving pathologist efficiency and extracting more information from tissues. In this review, we provide an overview of the main research directions intersecting with artificial intelligence and pathology in relation to oncology, such as tumor classification, the prediction of molecular alterations, and biomarker quantification. We then discuss examples of tools that have matured into clinical products and gained regulatory approval for clinical use. Finally, we highlight the main hurdles that stand in the way of the digitalization of pathology and the application of artificial intelligence in pathology while also discussing possible solutions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10705335PMC
http://dx.doi.org/10.3390/cancers15235692DOI Listing

Publication Analysis

Top Keywords

artificial intelligence
16
resource-scarce medical
8
medical systems
8
application artificial
8
digitalization pathology
8
intelligence pathology
8
pathology
7
breaking barriers
4
barriers ai's
4
ai's influence
4

Similar Publications

Weighted Echo State Graph Neural Networks Based on Robust and Epitaxial Film Memristors.

Adv Sci (Weinh)

January 2025

College of Physics Science & Technology, School of Life Sciences, Institute of Life Science and Green Development, Key Laboratory of Brain-Like Neuromorphic Devices and Systems of Hebei Province, Hebei University, Baoding, 071002, China.

Hardware system customized toward the demands of graph neural network learning would promote efficiency and strong temporal processing for graph-structured data. However, most amorphous/polycrystalline oxides-based memristors commonly have unstable conductance regulation due to random growth of conductive filaments. And graph neural networks based on robust and epitaxial film memristors can especially improve energy efficiency due to their high endurance and ultra-low power consumption.

View Article and Find Full Text PDF

The COVID-19 pandemic provided an ideal scenario for studying the care of the elderly population, we implemented a tool named the Geriatric Measure (GM) tool to determine the severity and need for hospitalization. The objective of the study is to evaluate if the results of a brief Geriatric Measure tool are associated with mortality and other outcomes among older adults with COVID-19 treated in the emergency department. Retrospective observational cohort study.

View Article and Find Full Text PDF

Machine learning techniques for non-destructive estimation of plum fruit weight.

Sci Rep

January 2025

Crop and Horticultural Science Research Department, Mazandaran Agricultural Resources Research and Education Center, Agricultural Research, Education and Extension Organization (AREEO), Tajrish, Iran.

Plum fruit fresh weight (FW) estimation is crucial for various agricultural practices, including yield prediction, quality control, and market pricing. Traditional methods for estimating fruit weight are often destructive, time-consuming, and labor-intensive. In this study, we addressed the problem of predicting plum FW using artificial intelligence (AI) methods based on fruit dimensions.

View Article and Find Full Text PDF

Cancer-associated fibroblasts (CAFs) significantly influence tumor progression and therapeutic resistance in colorectal cancer (CRC). However, the distributions and functions of CAF subpopulations vary across the four consensus molecular subtypes (CMSs) of CRC. This study performed single-cell RNA and bulk RNA sequencing and revealed that myofibroblast-like CAFs (myCAFs), tumor-like CAFs (tCAFs), inflammatory CAFs (iCAFs), CXCL14CAFs, and MTCAFs are notably enriched in CMS4 compared with other CMSs of CRC.

View Article and Find Full Text PDF

Graph data is essential for modeling complex relationships among entities. Graph Neural Networks (GNNs) have demonstrated effectiveness in processing low-order undirected graph data; however, in complex directed graphs, relationships between nodes extend beyond first-order connections and encompass higher-order relationships. Additionally, the asymmetry introduced by edge directionality further complicates node interactions, presenting greater challenges for extracting node information.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!