Background: Titanium (Ti) implants has been criticized for the tiring wait for osseointegration, often making the patient reconsider implant treatment. Surface treated Ti implants are emerging as a promising solution with superior osseointegration, early loading protocols and shortened period of edentulousness. The aim of this study is to assess the osseointegration of Ti surface coated with novel Cissus quandrangularis Chitosan Hydrogel (CqChH) compared to Commercially pure (Cp) implants.
Methods: 24 Cp Ti implants were divided into 2 subgroups (n = 12). The test group consisted of Ti implants surface treated with the novel hydrogel and control group consisted of Cp Ti implants. 3 % CqChH was prepared and was coated on the Ti implants prior to placement in the femur and tibial heads of rabbits. Implant Stability Quotient (ISQ) was recorded at the 6th and 12th week. Animals were sacrificed and subjected to Removal Torque Quotient (RTQ). The samples were retrieved en bloc and stained for histopathologic analysis. The collected data was subjected to statistical analysis using Unpaired student t-Test.
Results: At the end of 6th week CqChH coated implants did not show any statistically significant difference in both ISQ and RTQ values compared to Cp ones. However, at the end of the 12th week CqChH coated implants demonstrated significantly higher ISQ (73.91 ± 4.39) and RTQ (75.96 ± 14.10) compared to Cp ones.
Conclusions: This study demonstrated that the novel hydrogel coating applied to the implant's surface exhibited not only enhanced bone regeneration but also elicited a new bone formation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jormas.2023.101727 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Calcium phosphate-based anti-infective bone cements: recent trends and future perspectives.
Front Pharmacol
February 2025
Department of Orthopaedics, Second Affiliated Hospital, Air Force Medical University, Xi'an, China.
Bone infection remains a challenging condition to fully eradicate due to its intricate nature. Traditional treatment strategies, involving long-term and high-dose systemic antibiotic administration, often encounter difficulties in achieving therapeutic drug concentrations locally and may lead to antibiotic resistance. Bone cement, serving as a local drug delivery matrix, has emerged as an effective anti-infective approach validated in clinical settings.
View Article and Find Full Text PDFCitrus-Fruit-Based Hydroxyapatite Anodization Coatings on Titanium Implants.
Materials (Basel)
March 2025
Department of Biomedical Materials Science, University of Mississippi Medical Center, Jackson, MS 39216, USA.
The increasing demand for titanium implants necessitates improved longevity. Plasma-sprayed hydroxyapatite coatings enhance implant osseointegration but are susceptible to delamination. Alternatively, anodized hydroxyapatite coatings have shown greater adhesion strengths.
View Article and Find Full Text PDFStudy on the Preparation and Corrosion-Wear Properties of TiN/Sn Coatings on the Ti-25Nb-3Zr-2Sn-3Mo Titanium Alloy.
Materials (Basel)
March 2025
School of Materials and Architectural Engineering, Guizhou Normal University, Guiyang 550025, China.
Due to its excellent specific strength, corrosion resistance, and biocompatibility, titanium alloy is often used as a biological implant material. In order to address the issues of low hardness and poor wear resistance of the Ti-25Nb-3Zr-2Sn-3Mo titanium alloy, a TiN/Sn coating with good biocompatibility was deposited on its surface using a new composite modification technology of surface mechanical strengthening + surface mechanical coating. By taking advantage of the wear resistance of TiN and the adhesiveness of Sn, a composite coating with corrosion-wear resistance was formed to improve its corrosion-wear resistance.
View Article and Find Full Text PDFTotal femur replacement in revision arthroplasty for non-oncologic patients: a systematic review.
Eur J Orthop Surg Traumatol
March 2025
Department of Orthopaedic Surgery, University of California San Diego, 4150 Regents Park Row, La Jolla, CA, 92037, USA.
Purpose: Revision total joint arthroplasty cases including those complex enough to require limb-salvage procedures are expected to significantly increase. Total femoral replacements represent a limb-preserving procedure with potential utility for these complicated cases. This review seeks to summarize the outcomes of total femoral replacements when used in the revision arthroplasty setting.
View Article and Find Full Text PDFSafety and complications of antimicrobial coated compared to conventional intramedullary femoral nails in proximal femoral fractures.
Eur J Trauma Emerg Surg
March 2025
Klinik und Poliklinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig, Liebigstr. 20, Leipzig, 04103, Germany.
Purpose: The aim of this study was to compare one-year mortality and the incidence of complications, particularly fracture-related infections, between patients with proximal femur fractures treated with novel noble metal-coated implants and those treated with uncoated implants, to detect possible effects of the coating on these endpoints.
Methods: Design: Retrospective cohort observational study.
Setting: Level 1 trauma centre.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!