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State-Regulated Psychedelics on a Collision Course With FDA.
JAMA
December 2023
Project on Psychedelics Law and Regulation (POPLAR), Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard Law School, Cambridge, Massachusetts.
A Failure to Guide: Patient Experiences within a State-Run Cannabis Program in Pennsylvania, United States.
Subst Use Misuse
April 2022
Department of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Introduction: Medical cannabis has been available for purchase in dispensaries in Pennsylvania, United States since April 2018. Patients wanting to access medical cannabis must receive certification from physicians for a limited number of physical and psychological conditions. Despite increasing numbers of patients using cannabis in the United States, little is known about the patient experience during certification and entry into state-regulated cannabis programs and how and if they are guided by health care professionals and dispensary staff.
View Article and Find Full Text PDFEffects of cannabidiol in cannabis flower: Implications for harm reduction.
Addict Biol
January 2022
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Using a federally compatible, naturalistic at-home administration procedure, the present study examined the acute effects of three cannabis flower chemovars with different tetrahydrocannabinol (THC) to cannabidiol (CBD) ratios, in order to test whether chemovars with a higher CBD content produce different effects. Participants were randomly assigned to ad libitum administration of one of three chemovars (THC-dominant: 24% THC, 1% CBD; THC+CBD: 9% THC, 10% CBD; CBD-dominant: 1% THC, 23% CBD); 159 regular cannabis users (male = 94, female = 65) were assessed in a mobile pharmacology lab before, immediately after, and 1 h after ad libitum administration of their assigned chemovar. Plasma cannabinoids as well as positive (e.
View Article and Find Full Text PDFUsing wastewater-based analysis to monitor the effects of legalized retail sales on cannabis consumption in Washington State, USA.
Addiction
September 2019
Alcohol and Drug Abuse Institute, University of Washington, Seattle, WA, USA.
Aims: To perform a wastewater-based analysis to explore the impact of newly legalized retail cannabis sales on its use and to determine if this approach could estimate the size of the legal market place, which began 1 August 2014 in the study area.
Design: Laboratory study of raw wastewater samples collected and analyzed over the 3-year period from 2014 to 2016.
Setting And Participants: Samples obtained from the two wastewater treatment plants that serviced a municipality of 200 000 people in the state of Washington, USA.
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