Reverse Genetics Systems for Filoviruses.

Methods Mol Biol

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald, Insel Riems, Germany.

Published: December 2023

Filoviruses are causative agents of severe hemorrhagic fevers with high case fatality rates in humans. For studies of virus biology and the subsequent development of countermeasures, reverse genetic systems, and especially those facilitating the generation of recombinant filoviruses, are indispensable. Here, we describe the generation of recombinant filoviruses from cDNA.

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http://dx.doi.org/10.1007/978-1-0716-3533-9_1DOI Listing

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