AI Article Synopsis
- - The text discusses two PCR-based sequencing systems for studying respiratory syncytial virus (RSV): RSVAB-WGS for whole-genome sequencing and RSVAB-GF for targeting specific viral antigens, G and F.
- - RSVAB-GF is used to help analyze cases with low viral load, enhancing understanding of RSV's genetic diversity.
- - The goal of these methods is to inform molecular epidemiology, vaccine effectiveness, and treatment strategies, while standardizing surveillance in light of new vaccines.
Article Abstract
To advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for challenging cases with low viral load. These methods monitor RSV genetic diversity to inform molecular epidemiology, vaccine effectiveness and treatment strategies, contributing also to the standardisation of surveillance in a new era of vaccines.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10831411 | PMC |
| http://dx.doi.org/10.2807/1560-7917.ES.2023.28.49.2300637 | DOI Listing |
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