Measles seroprevalence in adolescents and young adults living with HIV and response to MMR booster in seronegative ones.

AIDS

Division of Pediatric Infectious Diseases, Department of Pediatrics, Escola Paulista de Medicina (EPM) - Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

Published: January 2024

Objective: The study analyzed people with HIV (PWH) measles seroprevalence and response to MMR booster given to seronegative individuals.

Design: A prospective cohort study with four groups: vertically (v-HIV), horizontally infected (h-HIV) individuals, and two control groups. An MMR booster was offered to seronegative individuals.

Results: Measles seropositivity and IgG antibodies were significantly lower in v-HIV than in the other groups. All measles seronegative patients responded to booster.

Conclusion: An MMR booster must be sought during adolescence in vertically PWH.

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Source
http://dx.doi.org/10.1097/QAD.0000000000003720DOI Listing

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