This comprehensive review aims to provide an overview of the pharmacological properties of erucic acid (EA) and highlight areas that require further research. EA is an omega-9 fatty acid found in certain vegetable oil, such as rapeseed oil has demonstrated favourable effects in rodents, including ameliorating myocardial lipidosis (fat accumulation in the heart muscle), congestive heart disease, hepatic steatosis (fat accumulation in the liver), and memory impairments. These findings have prompted regulatory bodies to establish limits on EA content in food oils. The studies were performed on rodents and led to caution on ingesting the EA at high levels. Moreover, EA is frequently utilized as a nutritional supplement for the treatment of adrenoleukodystrophy, myocardial disease, and memory improvement. The review of the article indicated that EA improves cognitive function, has a part in Huntington's disease, interacts with peroxisome proliferator-activated receptors, inhibits elastase and thrombin, has anti-inflammatory, antioxidant, and anti-tumour properties, and inhibits influenza A virus. This article elucidates the pharmacological effects of EA, an omega-9 fatty acid.
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http://dx.doi.org/10.1007/s00210-023-02875-x | DOI Listing |
BMC Plant Biol
January 2025
Department of Biotechnology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
Background: Preserving plant genetic resources is essential for tackling global food security challenges. Effectively meeting future agricultural demands requires comprehensive and efficient assessments of genetic diversity in breeding programs and germplasm from gene banks. This research investigated the diversity of pheno-morphological traits, along with the fatty acid and tocopherol content and composition, in 135 double haploid lines of camelina.
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January 2025
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.
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View Article and Find Full Text PDFFront Immunol
January 2025
University of Michigan, Department of Internal Medicine, Ann Arbor, MI, United States.
Introduction: Despite progress in systemic lupus erythematosus (SLE) treatment, challenges persist in medication adherence due to side effects and costs. Precision nutrition, particularly adjusting fatty acid intake, offers a cost-effective strategy for enhancing SLE management. Prior research, including our own, indicates that increased consumption of omega-3 polyunsaturated fatty acids (PUFAs) correlates with improved outcomes in SLE patients.
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December 2024
North Carolina Zoo, Asheboro, NC 27205, USA.
Flamingos in managed care are vulnerable to inflammatory states, including pododermatitis, trauma, and capture myopathy. Fatty acids are an important component of well-balanced nutrition and crucial to endogenous immune responses associated with these conditions, yet fatty acids have not been assessed in flamingos. This study reported complete whole blood circulating fatty acid profiles in two flamingo species in managed care receiving different diets.
View Article and Find Full Text PDFFront Microbiol
November 2024
Department of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
A multivariate nutritional analysis indicated that the consumption of erucic acid-rich food, a fatty acid (FA) found primarily in rapeseed and mustard oil, was positively correlated with higher counts of lactic acid bacteria (LAB). Furthermore, we showed N6.2, as well as other species of LAB tested from the former genus, were able to efficiently use erucic acid (EA) as the source of FA.
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