Oral doxycycline for early bleb leak after trabeculectomy: A case report and review of literature.

Oman J Ophthalmol

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, Glaucoma Service, All India Institute of Medical Sciences, New Delhi, India.

Published: October 2023

We report the adjuvant role of oral doxycycline therapy for the management of early bleb leaks post mitomycin-augmented trabeculectomy. Two glaucoma patients, who underwent trabeculectomy with mitomycin C, presented with a low intraocular pressure (IOP) in the early postoperative period. Both patients had moderately elevated bleb with Seidel's positive test. Oral doxycycline 100 mg twice daily was given for 1 week in addition to routine postoperative management. Post doxycycline therapy at 1 week, healing of the wound was noted, with a negative Seidel's test. The IOP was maintained at 3 months postoperatively in both patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697256PMC
http://dx.doi.org/10.4103/ojo.ojo_95_22DOI Listing

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