The common adverse effects of chemotherapy are the reason for the use of effective, natural drugs and targeted administration to specific areas. On the one hand, Quercetin (QC) has positive effects as a natural anticancer agent. On the other hand, FeO, as nanoparticles (NP) with clinical properties and high porosity, can be a suitable carrier for drug loading and controlled release. In this study, QC was encapsulated in a synthesized FeO/Starch/Polyvinyl alcohol nanocarrier (FeO/S/PVA NC). Characterization of the NC was done by Fourier transforms infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), vibrating sample magnetometer (VSM), zeta potential and Dynamic light scattering (DLS). The percentage of drug loading (DLE) and encapsulation efficiency (EE) of QC in the NC containing FeO nanoparticles was 47 % and 86.50 %, respectively, while it was 36 % and 73 % in the NC without FeO. QC profile release in acidic and natural mediums showed controlled release and pH dependency of the NC. Viability of L929 and HepG2 treated cells with the FeO/S/PVA/QC was demonstrated by MTT staining which was in agreement with flow cytometry. The results show that FeO/S/PVA is a suitable NC for the targeted delivery of QC as a drug against HepG2 cancer cells.
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http://dx.doi.org/10.1016/j.ijbiomac.2023.128626 | DOI Listing |
Sci Rep
January 2025
Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.
In this study, we report the synthesis of iron oxide nanoparticles (FeONPs) using micro-emulsion-hydrothermal method. By adjusting the synthesis temperature, we successfully produced FeO nanorods and nanospheres. In addition, the 2-octanol, and the surfactant cetyltrimethylammonium bromide served as a solvent in the synthesis process.
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January 2025
Department of Chemistry, Natural and Computational Sciences, Wolaita Soddo University, P. Box 138, Wolaita Soddo, Ethiopia.
A microbial fuel cell (MFC) is a modern, environmentally friendly, and cost-effective energy conversion technology that utilizes renewable organic waste as fuel, converting stored chemical energy into usable bioelectricity in the presence of a biocatalyst. Despite advancements in MFC technology, several challenges remain in optimizing power production efficiency, particularly regarding anode materials and modifications. In this study, low-cost biosynthesized iron oxide nanoparticles (FeO NPs) were coated with a polyaniline (PANI) conducting matrix to synthesize hybrid FeO/PANI binary nanocomposites (NCs) as modified MFC anodes via an in-situ polymerization process.
View Article and Find Full Text PDFBMC Microbiol
December 2024
Department of Physics, College of Science, University of Halabja, Halabja, Kurdistan Region, Iraq.
Background: Antimicrobial resistance (AMR) presents a serious threat to health, highlighting the urgent need for more effective antimicrobial agents with innovative mechanisms of action. Nanotechnology offers promising solutions by enabling the creation of nanoparticles (NPs) with antibacterial properties. This study aimed to explore the antibacterial, anti-biofilm, and anti-virulence effects of eco-friendly synthesized α-Fe₂O₃ nanoparticles (α-Fe₂O₃-NPs) against pathogenic bacteria.
View Article and Find Full Text PDFInorg Chem
December 2024
Facultad de Farmacia, Departamento de Química y Bioquímica, Urbanización Montepríncipe, Universidad San Pablo-CEU, CEU Universities, Boadilla del Monte, E-28668 Madrid, Spain.
Lanthanum strontium ferrite (LaSrAgFeO = 0; LSFO) and its silver-doped derivative (LaSrAgFeO = 0.05; LASFO) are synthesized using mild conditions by a sol-gel method. Both oxides present a perovskite-like structure with orthorhombic symmetry due to octahedral tilting; thus, the incorporation of silver in the A-site does not significantly modify the perovskite structure.
View Article and Find Full Text PDFNanoscale Adv
December 2024
Centre for Advanced Materials Joining, Department of Mechanical and Mechatronics Engineering, University of Waterloo 200 University Avenue West Waterloo Ontario N2L 3G1 Canada
Flexible and wearable devices play a pivotal role in the realm of smart portable electronics due to their diverse applications in healthcare monitoring, soft robotics, human-machine interfaces, and artificial intelligence. Nonetheless, the extensive integration of intelligent wearable sensors into mass production faces challenges within a resource-limited environment, necessitating low-cost manufacturing, high reliability, stability, and multi-functionality. In this study, a cost-effective fiber laser direct writing method (fLDW) was illustrated to create highly responsive and robust flexible sensors.
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