AI Article Synopsis
- Multiple doses of [Tl]TlCl were created using an electrodeposition method with a Cyclone-30 cyclotron, employing a proton energy of 28 MeV at a beam current of 50 μA for 8 hours.
- Semi-automated radiochemical separation and purification of [Tl]TlCl were achieved through Ion Exchange Column Chromatography (IECC) and liquid-liquid extraction techniques.
- The final product, [Tl]TlCl, was utilized for medical purposes in patients with coronary artery disease (CAD).
Article Abstract
Multiple patient doses of [Tl]TlCl has been produced using electrodeposited enriched Tl in 30 MeV cyclotron (Cyclone-30) with 28 MeV proton energy at 50 μA beam current for 8 h. Ion Exchange Column Chromatography (IECC) and liquid-liquid extraction has been employed for semi-automated radiochemical separation and purification of produced [Tl]TlCl. The produced [Tl]TlCl was used in coronary artery disease (CAD) patients.
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| http://dx.doi.org/10.1016/j.apradiso.2023.111128 | DOI Listing |
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